NDAOralTablet
Approved
Feb 2002
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
3
Mechanism of Action
1 -receptor histamine antagonist activity. Receptor binding data indicate that at a concentration of 2 to 3 ng/mL (7 nanomolar), desloratadine shows significant interaction with the human histamine H 1 receptor. Desloratadine inhibited histamine release from human mast cells in vitro . Results of a…
Clinical Trials (3)
LEADER (LEvocetirizine And DEsloratadine in Allergic Rhinitis)
Started Apr 2005
729 enrolled
Rhinitis, Allergic, Perennial
Fexofenadine (Allegra®) in Healthy Adults Who Have Been Identified as Slow Metabolizers for Desloratadine
Started Feb 2003
220 enrolled
Allergic Rhinitis
Fexofenadine HCl 180 mg, Desloratadine 5 mg and Placebo in Suppression of Wheal and Flare Induced by Histamine
Started Dec 2002
42 enrolled
Allergic Rhinitis