CLADRIBINE (cladribine) by Fosun Pharma is clinical pharmacology cellular resistance and sensitivity the selective toxicity of 2-chloro-2΄-deoxy-β-d-adenosine towards certain normal and malignant lymphocyte and monocyte populations is based on the relative activities of deoxycytidine kinase and deoxynucleotidase. Approved for active hairy cell leukemia, neutropenia, thrombocytopenia and 3 more indications. First approved in 2019.
Drug data last refreshed 20h ago
CLINICAL PHARMACOLOGY Cellular Resistance and Sensitivity The selective toxicity of 2-chloro-2΄-deoxy-β-D-adenosine towards certain normal and malignant lymphocyte and monocyte populations is based on the relative activities of deoxycytidine kinase and deoxynucleotidase. Cladribine passively…
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Purine Antimetabolite
Venetoclax in Combination With Cladribine and Cytarabine Alternating With Azacitidine Plus Venetoclax for the Treatment of Newly Diagnosed Monocytic AML and Active Signaling Mutated AML
A Study of Vemurafenib and Obinutuzumab Compared to Cladribine and Rituximab in People With Hairy Cell Leukemia (HCL)
Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)
Cladribine Venetoclax in Monocytic AML
Cladribine Tablets Level of Response Predictors in Clinical Practice (CLODINA)
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