NDAORALTABLET, CHEWABLE
Approved
Mar 2004
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
5
Data completeness
5/8 — Partial
CHILDREN'S ZYRTEC HIVES RELIEF (cetirizine hydrochloride) by Dr. Reddy's Laboratories is mechanism of actions cetirizine, a human metabolite of hydroxyzine, is an antihistamine; its principal effects are mediated via selective inhibition of peripheral h 1 receptors. Approved for urticaria, seasonal allergic rhinitis. First approved in 2004.
Drug data last refreshed 23h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Children's Zyrtec Hives Relief is an oral chewable tablet containing cetirizine hydrochloride, a selective peripheral H1-receptor antagonist antihistamine. It is indicated for urticaria and seasonal allergic rhinitis in pediatric patients. Cetirizine works by inhibiting histamine-mediated allergic responses without significant central nervous system penetration.
LOE Approaching
As LOE approaches, brand teams face portfolio pressure and declining resources; focus shifts to lifecycle extension or asset transition.
Mechanism of Action
Mechanism of Actions Cetirizine, a human metabolite of hydroxyzine, is an antihistamine; its principal effects are mediated via selective inhibition of peripheral H 1 receptors. The antihistaminic activity of cetirizine has been clearly documented in a variety of animal and human models. In vivo…
Indications (2)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.