CAPECITABINE

Post-LOE

capecitabine

ANDAORALTABLET
Approved
Apr 2020
Lifecycle
Post-LOE
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

Nucleic Acid Synthesis Inhibitors

Pharmacologic Class:

Nucleoside Metabolic Inhibitor

Clinical Trials (5)

NCT07413939Phase 2/3Not Yet Recruiting

RO7771950 Versus Tucatinib in Combination With Trastuzumab and Capecitabine in People With Locally Advanced or Metastatic Breast Cancer That is Human Epidermal Growth Factor Receptor 2 (HER2)-Positive

Started Apr 2026
650 enrolled
HER2-positive Breast Cancer
NCT07281768Phase 2Not Yet Recruiting

Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer

Started Mar 2026
66 enrolled
Colorectal Cancer
NCT07431281Phase 3Recruiting

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

Started Feb 2026
2,130 enrolled
Gastric CancerGastroesophageal Junction AdenocarcinomaEsophageal Cancer
NCT07222215Phase 2Recruiting

PhII Randomized CAPecitabine + ELAcestrant vs. Capecitabine Alone in ER+ Breast Cancer (CAPELA)

Started Jan 2026
297 enrolled
Estrogen-receptor-positive Breast CancerMetastatic Breast CancerBreast Cancer+6 more
NCT07407465Phase 2Recruiting

Upfront Trastuzumab-Deruxtecan Plus Capecitabine and Bevacizumab for Patients With HER-2 Positive Metastatic Colorectal Cancer.

Started Oct 2025
42 enrolled
Colorectal CancerColorectal AdenocarcinomaRectal Adenocarcinoma+4 more