BIVALIRUDIN IN 0.9% SODIUM CHLORIDE

Peak

bivalirudin

NDAINTRAVENOUSSOLUTION
Approved
Dec 2017
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
2

Mechanism of Action

anion-binding exosite of circulating and clot-bound thrombin. Thrombin is a serine proteinase that plays a central role in the thrombotic process, acting to cleave fibrinogen into fibrin monomers and to activate Factor XIII to Factor XIIIa, allowing fibrin to develop a covalently cross-linked…

Clinical Trials (2)

NCT02052635Phase 4Terminated

Ticagrelor vs Clopidogrel in Non-ST Elevation Acute Coronary Syndrome Patients Undergoing PCI With Bivalirudin.

Started Sep 2014
34 enrolled
Non-ST Elevation Acute Coronary Syndrome
NCT00464087Phase 3Completed

Switching From Fondaparinux to Bivalirudin or Unfractionated Heparin in ACS Patients Undergoing PCI

Started Jun 2007
100 enrolled
Acute Coronary Syndromes