BIAXIN

LOE Approaching

clarithromycin

NDAORALTABLETPriority Review
Approved
Oct 1991
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

CLINICAL PHARMACOLOGY Pharmacokinetics Clarithromycin is rapidly absorbed from the gastrointestinal tract after oral administration. The absolute bioavailability of 250 mg clarithromycin tablets was approximately 50%. For a single 500 mg dose of clarithromycin, food slightly delays the onset of…

Clinical Trials (5)

NCT06837259Phase 1Completed

A Study to Learn if Study Medicines Called Cyclosporine and Clarithromycin Affect How the Body Processes the Other Study Medicine Called PF-07328948 in Healthy Adults

Started Mar 2025
26 enrolled
Healthy Adults
NCT05965570Phase 1Completed

A Study to Investigate Effect of Clarithromycin, a Strong CYP3A4 Inhibitor, on Brensocatib Pharmacokinetics in Healthy Participants

Started Jul 2023
22 enrolled
Healthy Volunteers
NCT05633147Phase 1Completed

Effect of Clarithromycin on PK of Linaprazan, Linaprazan on PK of Clarithromycin and Linaprazan on PK of Midazolam

Started Nov 2022
35 enrolled
Safety IssuesPharmacokineticsDrug Interaction+1 more
NCT05469126Phase 1Completed

A Drug Interaction Study of Clarithromycin and LY3502970 in Healthy Participants

Started Aug 2022
26 enrolled
Healthy
NCT04843579Phase 2Terminated

Treatment of Selinexor in Combination With Clarithromycin, Pomalidomide and Dexamethasone for Relapsed Refractory Multiple Myeloma Patients

Started Dec 2021