BENDAMUSTINE HYDROCHLORIDE (bendamustine hydrochloride) by Fresenius Kabi is purine-like benzimidazole ring. Approved for within six months of treatment with rituximab, a rituximab-containing regimen, leukemia and 3 more indications.
purine-like benzimidazole ring. Mechlorethamine and its derivatives form electrophilic alkyl groups. These groups form covalent bonds with electron-rich nucleophilic moieties, resulting in interstrand DNA crosslinks. The bifunctional covalent linkage can lead to cell death via several pathways.…
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