NDAORALTABLET
Approved
Jul 1973
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
5/8 — Partial
BACTRIM DS (sulfamethoxazole and trimethoprim) by PharmaIN is dihydrofolate reductase inhibitors [moa]. Approved for prosthetic joint infection. First approved in 1973.
Drug data last refreshed 20h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
BACTRIM DS is a fixed-dose combination of sulfamethoxazole and trimethoprim, two synergistic dihydrofolate reductase inhibitors that block consecutive steps in bacterial nucleic acid synthesis. It is an oral antibiotic tablet approved in 1973 for treating prosthetic joint infections and other bacterial infections. This legacy product remains a cost-effective treatment option despite its age and approaching loss of exclusivity.
$0.019BPart D
LOE ApproachingDeclining
Minimal commercial opportunity; small team focused on generic transition and cost management rather than growth initiatives.
Mechanism of Action
Dihydrofolate Reductase Inhibitors
Pharmacologic Class:
Dihydrofolate Reductase Inhibitor Antibacterial
Indications (1)
Career Relevance
Working on BACTRIM DS offers limited career growth due to LOE approaching and minimal commercial spending. This role is best suited for professionals interested in generic transition strategy, cost-based marketing, or managed care negotiations rather than innovative drug development.
Brand Manager (defense/generic transition)
Worked on BACTRIM DS at PharmaIN? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.