Prosthetic Joint Infection
2
Pipeline Programs
3
Companies
5
Clinical Trials
0
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
2
0
0
0
Early DiscoveryClinical DevelopmentMarket
Competitive Landscape
3 companies ranked by most advanced pipeline stage
Osteal TherapeuticsTX - Dallas
2 programs2
VT-X7 Treatment System with Tobramycin SulfatePhase 21 trial
vancomycin hydrochloride and tobramycin sulfatePhase 21 trial
Active Trials
Heraeus MedicalAustralia - Unanderra
1 programGlobal cost of management of PJIN/A1 trial
Active Trials
J&
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
2027
2028
Osteal TherapeuticsVT-X7 Treatment System with Tobramycin Sulfate
Osteal Therapeuticsvancomycin hydrochloride and tobramycin sulfate
Johnson & JohnsonOral PCA
Johnson & JohnsonOral PCA
Heraeus MedicalGlobal cost of management of PJI
Clinical Trials (5)
Total enrollment: 225 patients across 5 trials
Abbreviated Protocol for Two-Stage Exchange
Start: Nov 2021Est. completion: Dec 2023
Phase 2Completed
Safety and Efficacy in Patients Treated for Hip or Knee PJI With Vancomycin and Tobramycin Joint Irrigation
Start: Oct 2018Est. completion: Aug 2020
Phase 2Completed
PCA Administration in Prosthetic Joint Infection
Start: Jan 2026Est. completion: Dec 2028100 patients
N/ANot Yet Recruiting
PCA Loading Time Before Knee Prosthetic Joint Infection Revision
Start: Mar 2025Est. completion: Dec 202510 patients
N/ANot Yet Recruiting
Cost Of Failure Following Reimplantation After a 2-Stage Exchange Strategy For Hip Or Knee Prosthetic Joint Infection
Start: Dec 2016Est. completion: Jul 2018115 patients
N/ACompleted
Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
3 companies competing in this space