NDANASALPOWDER
Approved
Apr 2025
Lifecycle
Growth
Competitive Pressure
0/100
Clinical Trials
1
Data completeness
5/8 — Partial
ATZUMI (dihydroergotamine mesylate) by Satsuma Pharmaceuticals is 5-ht 1dα and 5-ht 1dβ receptors. First approved in 2025.
Drug data last refreshed 2h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ATZUMI is a nasal powder formulation of dihydroergotamine mesylate, a 5-HT1D receptor agonist approved for acute migraine treatment. It works by constricting cranial blood vessels and reducing inflammation through serotonin receptor activation. The nasal powder delivery offers a non-injectable alternative to existing ergotamine therapies.
Growth15.3 years to LOE
Recently approved product in growth phase with opportunity for market penetration in acute migraine segment; early-stage team building likely underway.
Mechanism of Action
5-HT 1Dα and 5-HT 1Dβ receptors. The therapeutic activity of dihydroergotamine in migraine is generally attributed to the agonist effects at 5-HT 1D receptors.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Pharmacodynamic Study to Compare Acute Effects of Dihydroergotamine Mesylate (DHE) on Pulmonary Arterial Pressure
Started Mar 2010
24 enrolled
Healthy
Career Relevance
Working on ATZUMI offers entry into a recently launched specialty pharma product with clear growth trajectory and 15+ years of patent protection. The nasal delivery platform and acute indication present unique commercial and clinical challenges suited to entrepreneurial team-building environments.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.