ATHROMBIN

Pre-Launch

warfarin sodium

NDAORALTABLET

Lifecycle

Pre-Launch

Mechanism of Action

K-dependent clotting factors, which include Factors II, VII, IX, and X, and the anticoagulant proteins C and S. Vitamin K is an essential cofactor for the post ribosomal synthesis of the vitamin K-dependent clotting factors. Vitamin K promotes the biosynthesis of γ-carboxyglutamic acid residues in…

Indications (5)

pulmonary embolism atrial fibrillation further extension of the formed clot to prevent secondary thromboembolic complications possibly fatal sequelae

External Resources

DailyMed

Full prescribing information

FDA Drugs@FDA

FDA approval history

RxNorm

Drug nomenclature & identifiers