ASTELIN

LOE Approaching

azelastine hydrochloride

NDANASALSPRAY, METERED

Approved

Nov 1996

Lifecycle

LOE Approaching

Competitive Pressure

30/100

Clinical Trials

3

Mechanism of Action

CLINICAL PHARMACOLOGY Azelastine hydrochloride, a phthalazinone derivative, exhibits histamine H 1 -receptor antagonist activity in isolated tissues, animal models, and humans. Astelin Nasal Spray is administered as a racemic mixture with no difference in pharmacologic activity noted between the…

Indications (10)

the symptoms of seasonal allergic rhinitis such sneezing nasal pruritus in adults children 5 years older for the treatment of the symptoms of vasomotor rhinitis such nasal congestion postnasal drip in adults children 12 years

Clinical Trials (3)

NCT04264637Phase 3Completed

Study to Find Out How Long it Takes Azelastine Hydrochloride 0.15% Nasal Spray to Relieve Symptoms in Patients Suffering From Allergic Rhinitis

Started Feb 2020

110 enrolled

Allergic Rhinitis

NCT02249663Phase 3Unknown

Clinical Equivalence of Azelastine Hydrochloride and Fluticasone Propionate, 137/50 mcg Nasal Spray to Dymista™

Started Aug 2014

1,535 enrolled

Seasonal Allergic Rhinitis

NCT00612118Phase 2Completed

A Phase II Study Evaluating Intranasal GSK256066 and Azelastine Hydrochloride in Subjects With Seasonal Allergic Rhinitis

Started Feb 2008

70 enrolled

Allergic RhinitisRhinitis, Allergic, Seasonal

External Resources

Full prescribing information

FDA approval history

Drug nomenclature & identifiers