AMBIEN

LOE Approaching

zolpidem tartrate

NDAORALTABLET
Approved
Dec 1992
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
8

Mechanism of Action

short-term treatment of insomnia through binding to the benzodiazepine site of α1 subunit containing GABA A receptors, increasing the frequency of chloride channel opening resulting in the inhibition of neuronal excitation.

Indications (1)

Clinical Trials (5)

NCT05053620N/ACompleted

Astigmatism Correction With Intrastromal Arcuate Incisions in Eyes Undergoing Cataract Surgery With Femtosecond Laser Using the Cassini Ambient With Iris Registration (ARCUATAS)

Started Oct 2021
22 enrolled
CataractAstigmatism
NCT03025789Phase 3Completed

Fexinidazole in Human African Trypanosomiasis Due to T.b. Gambiense at Any Stage

Started Nov 2016
174 enrolled
Trypanosomiasis, AfricanSleeping SicknessTrypanosomiasis; Gambian
NCT00318448Phase 3Completed

Efficacy, Safety, and Tolerability of Ambien (Zolpidem) in the Treatment of Children Ages 6 to 17 With Attention Deficit Hyperactivity Disorder (ADHD)-Associated Insomnia

Started Apr 2006
201 enrolled
Attention Deficit Hyperactivity Disorder
NCT00296179Phase 4Completed

Ambien CR For Treatment Of Insomnia Associated With Depression When Used Concomitantly With Lexapro

Started Feb 2006
372 enrolled
Insomnia
NCT00296790Phase 4Completed

Ambien CR vs. Placebo For Treatment Of Insomnia Associated With Anxiety When Used Concomitantly With Escitalopram (Lexapro)

Started Feb 2006
372 enrolled
Insomnia