ALYFTREK

Growth

vanzacaftor, tezacaftor, and deutivacaftor

NDAORALTABLETPriority Review
Approved
Dec 2024
Lifecycle
Growth
Competitive Pressure
0/100
Clinical Trials
1

Mechanism of Action

Chloride Channel Activation Potentiators

Pharmacologic Class:

Cystic Fibrosis Transmembrane Conductance Regulator Potentiator

Clinical Trials (1)

NCT00953706Phase 2Terminated

Study of Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Homozygous for the F508del-CFTR Mutation

Started Sep 2009
140 enrolled
Cystic Fibrosis

Loss of Exclusivity

LOE Date
Jan 10, 2043
205 months away
Patent Expiry
Jan 10, 2043
Exclusivity Expiry
Dec 20, 2029

Patent Records (5)

Patent #ExpiryTypeUse Code
8354427
Jul 6, 2026
U-4091
9931334
Dec 28, 2026
Product
U-4080
8410274
Dec 28, 2026
Product
9670163
Dec 28, 2026
Product
U-4080
8754224
Dec 28, 2026
SubstanceProduct