NDAORALTABLETPriority Review
Approved
Jan 1964
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
22
Data completeness
4/8 — Partial
Priority Review
ALKERAN (melphalan) by Acrotech Biopharma is clinical pharmacology: melphalan is an alkylating agent of the bischloroethylamine type. Approved for multiple myeloma, lymphoma. First approved in 1964.
Drug data last refreshed 20h ago
Mechanism of Action
CLINICAL PHARMACOLOGY: Melphalan is an alkylating agent of the bischloroethylamine type. As a result, its cytotoxicity appears to be related to the extent of its interstrand cross-linking with DNA, probably by binding at the Nposition of guanine. Like other bifunctional alkylating agents, it is…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.