ABACAVIR SULFATE AND LAMIVUDINE
Growthabacavir sulfate; lamivudine
NDAORALTABLET, FOR SUSPENSION
Approved
Dec 2023
Lifecycle
Growth
Competitive Pressure
30/100
Mechanism of Action
Mechanism of Action: Abacavir is a carbocyclic synthetic nucleoside analogue. Abacavir is converted by cellular enzymes to the active metabolite, carbovir triphosphate (CBV-TP), an analogue of deoxyguanosine-5′-triphosphate (dGTP). CBV-TP inhibits the activity of HIV-1 reverse transcriptase (RT)…