ABACAVIR SULFATE AND LAMIVUDINE (abacavir sulfate; lamivudine) by Matrix Surgical USA is mechanism of action: abacavir is a carbocyclic synthetic nucleoside analogue. Approved for hiv-1 infection. First approved in 2023.
Drug data last refreshed 19h ago
Mechanism of Action: Abacavir is a carbocyclic synthetic nucleoside analogue. Abacavir is converted by cellular enzymes to the active metabolite, carbovir triphosphate (CBV-TP), an analogue of deoxyguanosine-5′-triphosphate (dGTP). CBV-TP inhibits the activity of HIV-1 reverse transcriptase (RT)…
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