Vice President, Biometrics

Position Summary

The Vice President of Biometrics will lead MBX Biosciences’ biometrics function, overseeing biostatistics, statistical programming, and data management to support clinical development programs from early-phase through regulatory submission. This strategic role ensures the integrity, quality, and compliance of all clinical trial data and analyses while driving innovation in data strategy and statistical methodologies. Reporting into our Chief Medical Officer, this individual will serve as a key member of the Clinical leadership team, partnering closely with Clinical Development, Clinical Operations, Regulatory Affairs, and other functions to enable data-driven decision-making and successful product development. 

Key Responsibilities

• Lead and build the Biometrics function, including biostatistics, programming, and data management, ensuring high-quality deliverables across all clinical programs.
• Oversee design and implementation of statistical methodologies for clinical trials.
• Ensure high quality and compliant biometric deliverables.
• Collaborate with cross-functional teams on protocols, statistical analysis plans, and data processes.
• Execute statistical analysis plans, ensuring statistical integrity and data consistency.
• Establish SOPs and best practices for innovative biometric strategies.
• Establish and maintain vendor partnerships ensuring quality and timely delivery of outsources biometrics activities.
• Support regulatory submissions and represent the company in agency interactions.
• Champion continuous improvement to enhance processes, systems, and compliance standards across the Biometrics function and organization.
• Other responsibilities as assigned.  

Qualifications

• Advanced degree (PhD or MS) in Biostatistics or related field
• 15+ years of biometrics experience within the biotech or pharmaceutical field.
• Proven track record of leading, building, and managing teams.
• Deep knowledge of clinical trial design, regulator requirements, and statistical software.
• Excellent problem-solving skills, strategic thinking, and ability to work in a fast-paced, collaborative environment.
• Outstanding scientific leadership and collaboration skills.  
• Outstanding interpersonal skills, self-awareness, and ability to manage team dynamics. 

Travel

You will be expected to travel periodically based on the needs of the business to the extent requested by the Company including attendance at Together Weeks, Together Days and functional meetings as requested by the Company.

Company Overview:

MBX Biosciences, Inc. (NASDAQ: MBX) is a clinical-stage biopharmaceutical company focused on the discovery and development of novel precision peptide therapies for the treatment of endocrine and metabolic disorders. The Company was founded by global leaders with a transformative approach to peptide drug design and development. Leveraging this expertise, the Company designed its proprietary Precision Endocrine Peptide™ (PEP™) platform to overcome the key limitations of unmodified and modified peptide therapies and to improve clinical outcomes and simplify disease management for patients. PEPs are selectively engineered to have optimized pharmaceutical properties, including extended time-action profiles and consistent drug concentrations with low peak-to-trough concentration ratios, consistent exposure to target tissues, and less frequent dosing. The Company is advancing a pipeline of novel candidates for endocrine and metabolic disorders with clinically validated targets, established endpoints for regulatory approval, significant unmet medical needs and large potential market opportunities. The Company’s pipeline includes its lead product candidate MBX 2109, in Phase 2 development for the treatment of chronic hypoparathyroidism (HP); MBX 1416, in Phase 1 development for the treatment of post-bariatric hypoglycemia (PBH); and an obesity portfolio that includes MBX 4291, as well as multiple discovery and pre-clinical candidates in development for the treatment of obesity. The Company is based in Carmel, Indiana. To learn more, please visit the Company website at www.mbxbio.com and follow us on LinkedIn. 

EEO Statement: 

MBX Biosciences is an Equal Opportunity Employer and is committed to treating all applicants fairly without discrimination. We welcome applications from all individuals, regardless of race, national origin, gender, age, physical characteristics, social origin, disability, union membership, religion, family status, pregnancy, sexual orientation, gender identity, gender expression or any unlawful criterion under applicable law.