Sr. Director, Cloud and Infrastructure Transformation

Use Your Power for Purpose

At the heart of Pfizer's Digital transformation sits Infrastructure & Cloud, enabling modern cloud infrastructure and engineering capabilities that influence business outcomes and provide value to our business, shareholders, and patients every day.
 

Pfizer is seeking an execution-focused Senior Director to lead transformational cloud and infrastructure initiatives that directly enable breakthrough science and drug discovery. You'll play a critical leadership role in developing our next-generation cloud platform for AI/ML-powered research while building and leading a high-performing technical team.
 

This role combines strategic thinking with hands-on delivery, technical depth with leadership impact, and the autonomy to make decisions that advance Pfizer's mission. Your work will provide the infrastructure foundation that enables our scientists to accelerate research, analyze complex data, and develop treatments that improve patients' lives.
 

Pfizer seeks individuals that are highly self-motivated, eager to learn, and effective when working in a team environment. A strong aptitude towards self-development, continuous learning, and growth is highly desired.

What You Will Achieve

The Senior Director, Cloud and Infrastructure Transformation provides executive-level technical leadership and strategic direction, playing a critical role in ensuring Pfizer continues to leverage cloud-native design patterns and modern infrastructure practices at enterprise scale. This role will help ensure our Infrastructure & Cloud organization delivers secure, compliant, productive, and innovative platforms that enable breakthrough science.
 

You will lead a team of 3-5 Directors and Senior Managers and Directors, providing strategic guidance, mentorship, and support in their professional development while driving the adoption of transformational cloud and infrastructure initiatives across the organization.

• Lead enterprise cloud and infrastructure transformation, including AI/ML platforms, data center migration, and network transformation

• Drive multi‑cloud, data center, and network initiatives with strong execution

• Make high‑impact architectural and technology decisions

• Provide senior technical leadership and shape infrastructure strategy

• Lead and develop senior leaders and high‑performing teams

• Partner with security, digital, and business stakeholders

• Operate effectively in a global, matrixed organization

• Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

 

Here Is What You Need (Minimum Requirements):

• Bachelor’s degree in information technology, Computer Science, Computer Engineering, or a similar discipline

• 12+ years in infrastructure, cloud, and networking with proven track record of delivering complex, multi-year transformation programs

• Deep multi-cloud expertise (AWS, Azure, GCP) with hands-on experience building production platforms at scale

• Comprehensive understanding of the full stack from on-premises data centers to cloud-native architectures

• Demonstrated success managing and developing senior technical leaders (Senior Managers, Directors)

• Extensive experience leading through influence in matrixed organizations, working across technical and business stakeholders

• Strong technical judgment shaped by real-world experience delivering at scale - hands-on when needed, strategic enough to delegate and orchestrate

• Expertise in modern cloud-native architectures, IaC (Terraform/OpenTofu), DevOps practices, automation, and security/compliance in regulated industries

• Excellent communicator with the ability to translate technical complexity for diverse audiences and drive alignment

• Proven ability to deliver results while managing multiple complex initiatives simultaneously

• Pragmatic decision-maker who balances ideal solutions with practical constraints and knows when to seek input or escalate
   

Bonus Points If You Have (Preferred Qualifications):

• AI/ML infrastructure experience, especially supporting research and data science workloads

• Background in pharma, biotech, or highly regulated industries

• Cloud certifications demonstrating depth of expertise

• Experience with large-scale migrations, datacenter exits, or M&A integrations

• Global team management across time zones and cultures

Other Job Details

• Last day to apply: May 28, 2026

• Work location assignment: Hybrid - onsite at NY Headquarters an average of 2.5 days per week or as the business requires

• 10-20% Travel

The annual base salary for this position ranges from $214,900.00 to $358,100.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

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