Description

Company Overview:

Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.

Role Summary:

The Senior Manager, US Medical Affairs supports execution of Dyne’s US Medical Affairs strategy for the Duchenne Muscular Dystrophy (DMD) program. This role contributes to critical launch readiness activities and supports the planning and delivery of US Medical initiatives, including KOL engagement, congress execution, medical education efforts, and cross-functional coordination.

The Senior Manager operates as both a scientific and operational contributor, helping prepare the US Medical organization for anticipated DMD program needs. This role partners closely with Medical Science Liaisons (MSLs), Global Medical Affairs, and cross-functional stakeholders to ensure medical activities are high-quality, compliant, and impactful.

This role is based in Waltham, MA.

Primary Responsibilities Include:

Medical Strategy Execution & Launch Readiness

Supports execution of US Medical Affairs tactical plans for the DMD program
Assists in implementing scientific platform materials, congress planning, and medical education initiatives
Contributes to cross-functional launch readiness activities to ensure alignment with program milestones
Supports development and deployment of DMD-focused scientific materials, disease state education resources, and field medical tools

Field Medical & KOL Engagement

Partners with the US MSL team to support KOL identification, engagement planning, insight gathering, and field metric tracking
Translates field insights into actionable recommendations for Medical Affairs and cross-functional teams
Tracks and monitors field activity and engagement effectiveness

Scientific Materials & Medical Review

Contributes to development of scientific materials, field tools, and educational content
Provides Medical review for promotional materials through the Promotional Review Committee (PRC)
Maintains deep and current scientific knowledge in DMD and Dyne’s therapeutic platform

Congress & External Engagements

Supports planning and execution of medical congresses, including onsite activities aligned to DMD milestones
Coordinates logistics and execution of US advisory boards and expert engagements

Cross-Functional Collaboration & Compliance

Partners with Patient Advocacy, Market Access, and Commercial teams to support aligned medical activities
Ensures all activities comply with US regulatory, legal, and compliance standards
Models Dyne’s core values through collaboration, accountability, and scientific integrity

Education and Skills Requirements:

Advanced scientific or clinical degree required (PhD, PharmD, MD, or equivalent)
7+ years of relevant Medical Affairs experience in pharmaceutical or biotechnology industry
Rare disease experience preferred; neuromuscular disease experience a plusExperience supporting US-based medical tactics, congress activities, or field medical programs
Strong scientific acumen with ability to translate clinical data for diverse audiences
Excellent written and verbal communication skills
Ability to operate effectively in a fast-paced, evolving environment with competing priorities
Demonstrated ability to build collaborative relationships with internal and external
to travel up to 25%, including occasional overnight and weekend travel
Positive team orientation with strong alignment to Dyne’s Core Values
Passion for improving the lives of patients with neuromuscular diseases

#LI-Onsite

MA Pay Range

$165,000—$190,000 USD

The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills.

The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.

Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.

Senior Manager, US Medical Affairs

Description

Company Overview:

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