MISSION
Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we’re looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously.
POSITION SUMMARY
The Senior Manager, Commercial IT Integration Lead is responsible for owning and operating Mirum’s Commercial IT integration landscape, serving as the enterprise lead for data movement, system connectivity, and integration governance.
This role has end-to-end accountability for the stability, scalability, monitoring, and continuous improvement of real-time, event-driven, and batch data flows supporting Salesforce Life Sciences Cloud (SFLC) and the broader Commercial ecosystem.
As the Patient CRM platform transitions to steady state, this role will expand to support broader Commercial IT integration strategy and data movement initiatives to strengthen Mirum’s enterprise data foundation. The Senior Manager, Commercial Integration Lead partners closely with the CRM Platform Lead, internal IT teams, business users, and external vendors to ensure integrations and data flows are reliable, scalable, and supportable in a regulated environment.
JOB FUNCTIONS/RESPONSIBILITIES
- Integration Platform Ownership & Leadership
- Serve as the IT owner for Commercial integrations, with accountability for enterprise integration architecture, standards, and governance.
- Define and enforce reusable integration patterns, API strategies, data contracts, and architectural guardrails across Commercial systems.
- Own the reliability, scalability, performance, and resiliency of real-time, event-driven, and batch integrations across Salesforce and external platforms.
- Partner closely with the CRM Platform Lead to ensure tight alignment between platform configuration, integration design, and data flow behavior.
- Contribute to long-term Commercial IT integration and data architecture strategy as the ecosystem matures.
- Integration Operations & Monitoring
- Establish proactive monitoring, alerting, health metrics, and observability frameworks across all Commercial integrations.
- Lead incident management, root cause analysis, and remediation for integration failures impacting Patient Services or HCP engagement operations.
- Design and implement structured error-handling, retry logic, and recovery patterns to minimize business disruption.
- Oversee integration change management, release coordination, and production support processes.
- Design, Optimization & Tool Strategy
- Refine and standardize integration patterns to improve reliability, performance, and ease of troubleshooting, independent of specific tools.
- Partner with IT leadership to evaluate, select, and recommend integration technologies as business and scalability needs evolve.
- Support initiatives to centralize and operationalize Commercial data assets, ensuring integration patterns align with enterprise data engineering and warehousing strategies.
- Ensure integration solutions are operationally supportable, well-documented, and resilient regardless of the underlying platform.
- Vendor & Cross-Functional Collaboration
- Work closely with internal IT teams, the SFLC Platform Lead, and external IT vendors to design, implement, and support integrations.
- Coordinate deployments, production support, and issue resolution across multiple vendors and system owners.
- Ensure effective knowledge transfer from implementation vendors to internal IT teams for long-term ownership.
- Governance, Security & Compliance
- Ensure integrations comply with Mirum’s security, data privacy, and regulatory requirements, including controlled data handling.
- Support audit readiness by maintaining integration documentation, data flow diagrams, and operational procedures.
- Implement and enforce governance practices for integration design, change management, and production support.
- Continuous Improvement & Enablement
- Identify opportunities to improve automation, observability, and operational efficiency across the integration landscape.
- Document integration architectures, support processes, and troubleshooting guides to enable consistent operations.
- Support evolving Commercial IT data needs, enabling scalable data movement and accessibility for reporting, analytics, and operational insight.
- Stay current with integration best practices and emerging technologies, recommending improvements that reduce risk and manual effort.
QUALIFICATIONS
- Bachelor’s degree in Computer Science, Information Systems, Engineering, or a related field.
- 6+ years of experience designing and supporting enterprise integrations in complex environments.
- Proven experience supporting Salesforce integrations across real-time and batch processing models.
- Hands-on experience with iPaaS or middleware platforms (e.g., Workato, MuleSoft, Informatica, or equivalent).
- Exposure to enterprise data engineering, data warehousing, or Commercial analytics ecosystems preferred.
- Experience working in biotech, pharma, or similarly regulated industries strongly preferred.
- Demonstrated experience working with external vendors and supporting platforms post–implementation.
Knowledge, Skills and Abilities:
- Deep expertise in enterprise integration architecture, including API-led design, event-driven patterns, middleware platforms, and batch processing models.
- Strong understanding of data governance, master data principles, and integration impacts on analytics and reporting ecosystems.
- Proven ability to implement observability frameworks, structured error handling, and resilient integration designs in production environments.
- Experience operating integrations in regulated industries, with awareness of validation principles, audit readiness, and secure data handling practices.
- Strong troubleshooting and analytical skills in high-availability production environments.
- Demonstrated leadership and cross-functional collaboration skills, balancing strategic integration roadmap ownership with hands-on operational accountability.
The salary range for this position is $190,000 to $205,000 USD. Compensation will be determined based on several factors including, but not limited to; skill set, years of experience, and the employee’s geographic location. Please note that the required compensation details listed in US role postings reflect the base salary only, and do not include bonus, equity, or benefits unless otherwise provided.
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Mirum Pharmaceuticals is committed to Equal Employment Opportunity (EEO) and to compliance with all Federal, State and Local laws that prohibit employment discrimination on the basis of race, age, national origin, ethnicity, religion, gender, gender identity, pregnancy, marital status, sexual orientation, citizenship, genetic disposition or characteristics, disability, veteran’s status or any other classification protected by applicable State/Federal/Local laws.
Mirum Pharmaceuticals provides reasonable accommodation for qualified individuals with disabilities and disabled veterans in job application procedures.