Senior Director, Global Obesity Commercial

ROLE SUMMARY
The Senior Director, Global Obesity Commercial Development serves as a senior strategic leader responsible for shaping Pfizer’s portfolio-level commercial development strategy for the global obesity franchise. This role leads cross-functional strategic integration, drives end-to-end commercial strategy across multiple pipeline assets and indications, and partners with senior leadership on high-impact decisions.

Operating as a senior strategic leader, this role requires a high sense of urgency, the ability to navigate significant ambiguity, and the capability to fluidly shift between asset‑level detail and portfolio‑wide strategic direction. The Senior Director must demonstrate exceptional cross‑functional leadership and communication skills, orchestrating complex integrations across clinical, commercial, and operational stakeholders. As the obesity portfolio progresses toward late‑stage development and early commercialization, this position is critical in ensuring portfolio‑level strategic coherence, enterprise‑aligned decision‑making, and executional readiness across the franchise. A successful candidate will bring deep scientific and business acumen, strong strategic judgment, and a demonstrated ability to influence senior leaders and governance bodies.

ROLE RESPONSIBILITIES
Portfolio-Level Commercial Strategy Leadership

• Lead the shaping of Pfizer’s overarching commercial vision and long-range portfolio strategy.
• Translate market and clinical signals into portfolio-level implications and strategic choices.
• Partner with R&D, Commercial, Finance, and BD to influence investment and lifecycle strategies.
• Oversee forecasting frameworks and scenario planning.
• Identify and shape BD opportunities.

Launch Readiness & Cross-Functional Integration

• Lead global launch readiness strategy across multiple assets and indications.
• Serve as senior integrator across Commercial, R&D, GAV, PGS, BD, and regions.
• Shape capabilities and operating model required to deliver strategy.
• Ensure alignment across global, regional, and market stakeholders.

QUALIFICATIONS

• Bachelor’s degree required; advanced degree strongly preferred.

Experience

• 12+ years in commercial and R&D strategy, commercial development, portfolio strategy, or consulting.
• Strong scientific background
• Leadership shaping end-to-end strategy across multiple assets.
• Strong financial acumen and experience influencing senior leadership.
• Exceptional communication and executive presence.
• Obesity or cardiometabolic experience strongly preferred.

 

 LAST DAY TO APPLY: 11/12/2026

 

 

The annual base salary for this position ranges from $214,900.00 to $358,100.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

 

 

 

 

 

 

This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.

 

 

Relocation assistance may be available based on business needs and/or eligibility.

 

 

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

 

 

 

 

 

 

To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.

 

 

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