Senior Director (QSP), Clinical Pharmacology & Pharmacometrics, Research Business Insights/Information Technology
Bristol Myers Squibb
This listing was originally posted on Bristol Myers Squibb's careers page. Formulate is an equal opportunity job aggregator and is not involved in the hiring process. Where salary information is estimated, it is derived from BLS industry benchmarks and may differ from actual compensation.
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Upgrade to Pro — $25/moAt Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.
Role Overview
Bristol Myers Squibb is seeking a strategic, scientifically grounded leader to serve as the Senior Director for Clinical Pharmacology & Pharmacometrics. This leader will partner deeply with Clinical Pharmacology, Pharmacometrics, Quantitative Pharmacology, and Translational Medicine stakeholders to deliver the applications, modeling environments, workflow automation, and governed operational capabilities that support CPP work end to end—from quantitative preclinical-to-clinical bridging through clinical PK/PD, dose and regimen decisions, and submission-support outputs.
This role supports the quantitative CPP layer across Research and Development, including pharmacometric workflows, clinical PK/PD systems, modeling platforms, reporting automation, regulatory evidence generation, and the governed operational capabilities required to run these workflows at scale.
Reporting to the Vice President, Research Business Insights & Technology, this leader will operate as part of a unified BI&T leadership team and act as a trusted partner to Research and Development leadership. The role carries accountability for the reliability, fit-for-purpose evolution, and long-term scaling of the CPP technology stack and workflow ecosystem, while working in a highly matrixed model with scientific leaders, data teams, lab-platform teams, and regulatory-facing partners.
Mission & Impact
Provide a scalable application and workflow backbone for CPP across preclinical-to-clinical translation, clinical PK/PD, dose selection, exposure-response, and model-informed development decisions
Improve the speed, quality, reproducibility, traceability, and inspection-readiness of pharmacometrics and clinical pharmacology workflows
Strengthen regulatory submissions through robust reporting, reusable quantitative evidence generation, and auditable outputs that support documents such as clinical pharmacology summaries and model-based appendices
Enable governed automation of priority CPP workflows, including reporting, simulation, execution, review, and knowledge reuse
Create a durable technology foundation for end-to-end CPP that can scale with pipeline demand and integrate cleanly across the broader Research and Development ecosystem
Sub-Areas in Scope
Clinical pharmacology and pharmacometrics applications, including population PK, PK/PD, exposure-response, dose optimization, and model-informed decision support
PBPK, QSP, drug-drug interaction, and other quantitative modeling environments used in CPP workflows
Clinical PK/PD systems and operational tooling that support end-to-end CPP execution
CPAR, Quarto-based or similar reporting automation, and submission-support workflows for quantitative regulatory deliverables
Quantitative translational workflows that bridge preclinical and clinical evidence in support of CPP decision-making
Workflow governance, audit trails, validation support, access controls, and inspection-ready operational practices for regulated quantitative environments
AI-enabled and advanced analytics capabilities that improve CPP workflow efficiency, simulation, review, reporting, and knowledge reuse
In partnership, but not sole ownership: translational labs, pathology, molecular and imaging lab workflows, CLIA-oriented lab operations, precision medicine diagnostics, and broad bioanalytical capabilities
Key Responsibilities
Serve as the single BI&T point of accountability for CPP technology, applications, workflows, and support services end to end
Partner across Research and Development to integrate CPP workflows with the scientific, data, and operational capabilities required for model-informed drug development
Own clinical pharmacology and pharmacometrics applications, modeling environments, reporting workflows, and operational support for core CPP use cases
Ensure operational excellence, reliability, governance, and continuous improvement across modeling environments, clinical PK/PD systems, reporting workflows, and submission-support applications
Lead automation of priority CPP workflows, including model execution, reporting, simulation, traceability, review, and evidence reuse
Support quantitative regulatory deliverables through fit-for-purpose tooling, reproducible workflows, and inspection-ready practices
Partner with Unified Lab & Experimental Platforms, Target & Disease Biology, and In-Vivo & Non-Clinical Pharmacology where translational science, lab systems, diagnostics, biomarker workflows, or bioanalytical capabilities intersect with CPP needs
Partner with the R&D Data organization on underlying data-product strategy, integration, and fit-for-purpose data access
Lead and grow a team of scientific technologists, product leaders, and specialized engineers aligned to this domain
Required Experience & Qualifications
Ph.D. in Pharmacometrics, Clinical Pharmacology, Pharmaceutical Sciences, Biostatistics, or related quantitative field
12+ years in pharmaceutical R&D with deep clinical pharmacology, pharmacometrics, and model-informed drug development experience
Proven experience implementing or leading CPP applications, PBPK and QSP environments, clinical PK/PD systems, or quantitative workflow automation
Demonstrated experience supporting regulatory submissions, quantitative reporting, and governed workflows in Development-facing settings
Experience applying AI/ML or advanced automation to quantitative modeling, reporting, or regulated scientific workflows is preferred
Director or Senior Director-level leadership experience; experience building and scaling a specialized scientific technology team is a strong differentiator
Critical Capabilities
Scientific Depth in Clinical Pharmacology and Pharmacometrics — Deep credibility with quantitative scientists and domain leaders across CPP
Strategic Partnership — Translates scientific and Development needs into practical, integrated technology and workflow solutions
Operational Leadership — Builds reliable, scalable, inspection-ready environments and support models for critical quantitative workflows
Regulatory Translation Capability — Understands how quantitative evidence is prepared, reported, reviewed, and used in regulatory settings
Leadership & Change Attributes
Strong partnership with senior scientific, clinical, and regulatory leaders
Comfort operating with regulatory and global Development stakeholders
Ability to recruit, develop, and retain highly specialized quantitative talent in a competitive market
Experience navigating matrixed organizations and building credibility quickly
Commitment to building a collaborative, high-performing culture in a growing team
What Differentiates Top Candidates
Experience as a clinical pharmacology or pharmacometrics technology leader inside a top-tier pharmaceutical R&D organization
Track record of applications, workflows, or platforms that improved dose selection, quantitative decision-making, or regulatory execution in Development-facing settings
Experience deploying workflow automation, AI-enabled capabilities, or advanced analytics in support of end-to-end CPP modeling, reporting, and decision-support operations
Demonstrated success building a specialized function from foundational capability to scaled organizational value while operating through strong matrix partnerships
We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.
Compensation Overview:
The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.
Benefits:
Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).
U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year.
Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays.
Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day.
U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits
How We Work
Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.
Supporting People with Disabilities
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.
Candidate Rights
BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/
Data Protection
We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection.
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
If this posting is missing required information required by local law or incorrect, contact BMS at TAEnablement@bms.comwith the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.
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