Calyxo, Inc. is a medical device company headquartered in Pleasanton, California, USA. The company was founded in 2016 to address the profound need for improved kidney stone treatment. Kidney stone disease is a common, painful condition that consumes vast amounts of healthcare resources each year. Our team is led by executives and investors with a proven track record of commercializing paradigm-shifting devices to meet unmet needs within urology.
Are you ready to change the future of kidney stone treatment? We are seeking high achievers who want to be part of a dynamic team working in a fun, diverse atmosphere.
Summary:
As the Sr. Buyer, you will have end-to-end (cradle-to-grave) ownership of procurement execution and outcomes for assigned commodities, suppliers, and Contract Manufacturers (CMs). This role is accountable for material availability, supplier and CM execution performance, inventory health, and cost effectiveness, operating within established category strategies and commercial frameworks defined by Category Management. The Sr. Buyer partners cross-functionally and externally to ensure supply continuity, scalability, and compliance while delivering measurable execution-level procurement results that support manufacturing operations, product changes, and business growth.
In This Role, You Will:
Cradle-to-Grave Procurement Execution Ownership
- Own the full procurement execution lifecycle (cradle-to-grave) for assigned scope—from purchase order execution and delivery through issue resolution, performance management, and close-out.
- Serve as the single point of accountability for supplier and CM execution, ensuring cost, quality, delivery, and service objectives are met throughout the lifecycle of parts and programs.
- Negotiate and procure materials, components, equipment, supplies, and services within established category strategies, contracts, and commercial frameworks defined by Category Management.
Sourcing Collaboration and Support, including Supplier Selection and Negotiations
- Collaborate with Calyxo Sourcing teams on supplier selection, negotiations, and implementation
- Support spot buys and tactical supplier identification and purchasing
- Cross-train with Sourcing teams to act as support and backup roles on the sourcing team, as needed
Planning, Ordering, and Execution Discipline
- Plan, execute, and monitor purchase orders using MRP, Kanban, Blanket POs, reschedules, and other appropriate planning techniques to meet production requirements.
- Execute pull-ins, push-outs, cancellations, and expedites at minimal total cost while protecting continuity of supply.
- Process returns to suppliers and ensure applicable credits are applied.
- Work closely with Receiving, Finance, and suppliers to reconcile discrepancies in receiving and invoicing.
Contract Manufacturer (CM) Execution Management
- Actively manage Contract Manufacturers (CMs) as an extension of Calyxo’s manufacturing operations, ensuring material readiness, capacity alignment, and execution to production requirements.
- Partner with CMs to support scale-up, engineering changes, and product transitions, ensuring sourcing execution, lead times, and inventory plans remain aligned to demand.
- Collaborate with Supply Chain, Quality, and Engineering to assess CM execution performance, drive corrective actions, and ensure timely implementation of agreed improvements.
- Support supplier or CM transitions and implementations led by Category Management, ensuring effective execution and continuity of supply.
Inventory Strategy Execution & Forecast Alignment
- Own inventory execution strategies for assigned materials, balancing service levels, working capital, lead times, and demand variability within defined inventory policies.
- Monitor and adjust inventory targets to prevent shortages and excess, proactively identifying risks and executing mitigation actions.
- Review forecasts with key stakeholders, integrate feedback, and ensure supply execution remains aligned to demand and operational priorities.
Supplier Performance, Quality Partnership, and Compliance
- Monitor supplier and CM execution performance and ensure compliance with released specifications, contracts, and quality requirements.
- Escalate and manage supplier or CM issues with structured follow-up and recovery plans.
- Participate in supplier sourcing events, assessments, and audits in support of Category Management–led strategies, working closely with the Supplier Quality Engineer (SQE).
- Maintain accurate supplier files and purchasing system data to support execution discipline and data integrity.
- Visit suppliers and CMs as needed to support execution performance and issue resolution.
Cost Improvement & Continuous Improvement
- Identify and deliver execution-driven cost savings and cost-avoidance opportunities while maintaining supply continuity and compliance.
- Create, improve, and follow purchasing processes and work instructions; drive transaction discipline and adherence to purchasing policies and company standards of conduct.
KPI Ownership & Cross-Functional Communication
- Own execution-level procurement KPIs for assigned suppliers and parts, including on-time delivery recovery, supplier and CM performance, inventory effectiveness, and execution-related cost savings.
- Analyze performance trends, identify root causes, and implement corrective actions to improve results.
- Provide timely, proactive communication to cross-functional stakeholders regarding risks, constraints, and mitigation plans.
- Perform other duties and special projects as assigned.
Who You Will Report To:
- Sr. Director, Supply Chain
Requirements:
- Bachelor’s Degree in Business Administration or equivalent Buyer/Purchasing experience.
- Minimum 8 years of experience supporting a manufacturing environment; medical device experience preferred.
- Experience in production control, material demand planning, or supply chain management.
- Strong working knowledge of modern ERP/MRP systems.
- Advanced Excel skills (pivot tables, macros, managing large data sets).
- Strong ability to communicate and partner cross-functionally with Engineering, Manufacturing, R&D, Finance, Quality, suppliers, and Contract Manufacturers.
- Highly organized with the ability to manage multiple priorities independently; motivated, detail-oriented, and execution-focused.
- On-site role in Pleasanton, CA; travel less than 5%; full-time employment.
What We Offer:
At Calyxo, you will be part of a knowledgeable, high-achieving, experienced, and fun team. You will work in a diverse work environment with experienced, proven leaders and have an opportunity to shape our company culture. You will experience constant learning and dynamic challenges to help you grow and be the best version of yourself.
We also offer an attractive compensation package, which includes:
- A competitive base salary range of $135,000 - $145,000 and variable incentive plan
- Stock options – ownership and a stake in growing a mission-driven company
- Employee benefits package that includes 401(k), healthcare insurance and paid vacation
Calyxo is deeply committed to fostering an environment where diversity and inclusion are not only valued but also prioritized. We believe a diverse and inclusive community empowers us to act courageously, care deeply, and dream boldly to impact people in big ways. Diverse viewpoints bring diverse capabilities, which strengthen our focus and fuel our growth.
Calyxo is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status or any other applicable legally protected characteristics
Legal authorization to work in the United States is required. In compliance with federal law, all persons hired will be required to verify their identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire.
Disclaimer:
At Calyxo, we prioritize a transparent and structured interview process to ensure the best fit for both our candidates and our team. Please be aware of the following:
- Structured Interview Process: Our hiring process includes multiple stages of interviews where you will have the opportunity to communicate directly with Calyxo employees. This ensures that you gain a comprehensive understanding of the role and our company culture.
- Verification of Identity: We do not extend job offers without first meeting candidates, either virtually or in person. This step is crucial to maintain the integrity of our hiring process and to ensure mutual alignment.
- Beware of Scams: Calyxo will never request sensitive personal information, such as your full name, address, phone number, or identification documents, via email or online forms before an official interview. Calyxo representatives will always contact you using an email format of firstname.lastname@calyxoinc.com. If you receive a request for information from any other domain, please contact us directly at info@calyxoinc.com to verify the legitimacy of the communication.
We appreciate your interest in joining Calyxo and look forward to getting to know you through our official channels.