Medical Director, US Medical Affairs

<div class="content-intro"><h3>Company Overview:</h3> <p>Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at <a href="https://www.dyne-tx.com/">https://www.dyne-tx.com/</a>, and follow us on <a href="https://x.com/dyne_tx">X</a>, <a href="https://www.linkedin.com/company/dynetx/">LinkedIn</a> and <a href="https://www.facebook.com/DyneTherapeutic/">Facebook</a>.</p></div><p><strong>Role Summary:</strong></p> <p data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"><span data-contrast="auto">The US Medical Director of Medical Affairs leads Dyne’s medical strategy and execution within the United States, focusing on launch readiness, US-specific KOL engagement, congress planning and execution, and supports real-world evidence (RWE) initiatives. This role ensures alignment with global strategy while tailoring activities to US regulatory, payer, and healthcare landscapes. This role leads efforts to communicate and disseminate scientific and clinical information, engage with medical professionals in the field and contribute to the overall success of the company’s portfolio. The US Medical Director collaborates closely with Global Medical Affairs, US Commercial, Regulatory, Market Access, and Clinical teams to drive successful product introduction and lifecycle management in the US market. </span><span data-ccp-props="{}"> </span></p> <p data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"><span data-contrast="none">This role is located in our Waltham, MA office.</span></p> <p data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"><strong><span data-contrast="none"><span data-ccp-parastyle="Body" data-ccp-parastyle-defn="{"ObjectId":"b669530d-9cee-5fd4-8da3-4cdbed7bfaa2|1","ClassId":1073872969,"Properties":[469775450,"Body",201340122,"2",134233614,"true",469778129,"Body",335572020,"1",469777841,"Helvetica",469777842,"Helvetica",469777843,"Helvetica",469777844,"Helvetica",469769226,"Helvetica",335551500,"0",268442635,"22"]}">Primary Responsibilities</span><span data-ccp-parastyle="Body"> Include</span><span data-ccp-parastyle="Body">:</span></span></strong><span data-ccp-props="{"335559739":120}"> </span></p> <ul> <li><span data-contrast="auto">Develop and execute US Medical Affairs strategy aligned with global objectives and US market needs</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Act as point person for all US Medical Affairs launch readiness activities, including working closely with global medical director and scientific communications on development of scientific platform development, local congress planning, and local medical education programs</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Support congress strategy execution in the US, including booth activities, symposia, and scientific presentations</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Work closely and with the Head of the Medical Science Liaison (MSL) team on US KOL engagement strategy: identify, map, and build relationships with key US experts</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Support insight collection and synthesis, and supporting the development of field material, working with the MSL team</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Develop US Medical Affairs advisory board strategy and organize and execute advisory boards and expert panels</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Work collaboratively with HCP and Patient Marketing as well as cross-functional stakeholders to integrate medical perspectives into brand strategy, ensuring alignment with scientific and commercial objectives</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Partner with Clinical Development and Clinical Operations to support US trial site engagement and recruitment strategies</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Working with the Global Medical Director, identify opportunities to generate real-world evidence (RWE) and phase IV data to address data gaps and support HCP and payer treatment decisions</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Ensure compliance with US regulatory and legal requirements for all medical activities</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Serve as subject matter expert on neuromuscular diseases and Dyne’s therapeutic platforms for US stakeholders</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Support the review and approval of externally presented materials through the Medical Review committee and Promotional Review Committee </span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Act as a role model for integrity and compliance in all interactions</span><span data-ccp-props="{}"> </span></li> </ul> <p data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"><strong><span data-contrast="none"><span data-ccp-parastyle="Body">Education</span><span data-ccp-parastyle="Body"> and Skills Requirements</span><span data-ccp-parastyle="Body">:</span></span></strong><span data-ccp-props="{"335559739":120}"> </span></p> <ul> <li><span data-contrast="auto">Doctorate degree (MD, PhD, PharmD) with experience in rare diseases; neuromuscular experience preferred</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Minimum 8 years of relevant experience in Medical Affairs within the US pharmaceutical/biotech industry</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Proven ability to lead US launch readiness and medical strategy execution</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Excellent communication and relationship-building skills with US KOLs and cross-functional teams</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Ability to interpret and communicate complex scientific data to diverse audiences</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Effective communication skills (written, verbal and presentation)</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Must be willing to travel up to 30%, inclusive of overnight and occasional weekends to meet with customers, internal stakeholders and attend relevant conferences </span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Candidates must be authorized to work in the U.S.</span><span data-ccp-props="{"201341983":0,"335559739":160,"335559740":259,"335572071":0,"335572072":0,"335572073":4278190080,"335572075":0,"335572076":0,"335572077":4278190080,"335572079":0,"335572080":0,"335572081":4278190080,"335572083":0,"335572084":0,"335572085":4278190080,"335572087":0,"335572088":0,"335572089":4278190080,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> <li><span data-contrast="auto">Positive team member who embodies Dyne’s Core Values</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Excitement about Dyne’s vision and mission </span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Experience managing direct reports </span><span data-ccp-props="{}"> </span></li> </ul><div class="content-pay-transparency"><div class="pay-input"><div class="title">MA Pay Range</div><div class="pay-range"><span>$196,000</span><span class="divider">—</span><span>$285,000 USD</span></div></div></div><div class="content-conclusion"><p> </p> <p>The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills.</p> <p>The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements.  Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.</p> <p class="Body"><em><span style="font-family: 'Arial',sans-serif; color: #626262;">Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.</span></em></p></div>