Global Development Medical Director

As a Global Development Medical Director with a focus on Cardiovascular/Renal or Metabolic dysfunction (including Diabetes, Obesity and NASH/MASH), you play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives. The Global Development Medical Director in Late Phase CVRM (Cardiovascular, Renal, and Metabolic diseases) is responsible for the design, conduct, monitoring, data interpretation and reporting of individual clinical trials ensuring that the clinical data collected within the study will allow determination of the benefits and risks of the compound, as well as allow for the intended label indication and price in markets globally. The individual operates according to the highest ethical standards to align with internal SOPs, local regulations, laws, Good Clinical Practice, and regulatory requirements.

Medical expert accountabilities

• Provide strategic medical and scientific knowledge and support the design, initiation, execution, completion, and interpretation of a clinical study

• Accountable to deliver medical information, answers, and clarifications to Regulators, Ethics Committees, Marketing Companies, Investigators/Sites

Trial conduct and hands-on delivery accountabilities

• Accountable to the Global Clinical Head (GCH) for the medical aspects and design of studies. Also responsible for driving decisions within Study Team (ST) remits together with other ST members and for solving medical issues with the study team

• Oversight of medical and ethical components of studies including patient safety in compliance with GCP

• Deliver all relevant study documents (e.g Protocol, Amendments, Statistical Analysis Plan, Informed Consent Form, Case Report Forms, and Safety and Risk-Based Monitoring Plans)

• Conduct safety surveillance on a study level including the process for Adverse Events (AE)/ Serious AE reporting, the querying of missing/unclear data, the review of blinded safety data, and escalation to the GCH/Global Safety Physician when needed

• Medically accountable for international investigator meetings, and support Marketing Companies in national activities

• Approve, with the GCH, the Clinical Study Report; including preparation and production (Introduction, Results, Discussion)

Messaging and external impact accountabilities

• Maintain a high degree of understanding and awareness of new and emerging medical developments, globally

• Apply strategic intent when working with Alliance partners, Regulatory Authorities, payers, opinion leaders, prescribers and consumers of AstraZeneca products

• Provide guidance for investigator-initiated trials in collaboration with regional marketing companies 

Basic Qualifications:

• Graduate of a recognized school of medicine with an M.B.B.S. or M.D. degree with specialty or experience in the Cardiovascular, Renal or Metabolism (including obesity, diabetes, MASH) therapeutic areas, 

• 3+ years of pharmaceutical industry experience OR 3+ years of clinical research experience in the academic or clinical practice setting

• Demonstrated partnership and collaboration skills, including acting as the leader and clearly communicating across countries and cultures 

• Fluent in oral and written English, with good presentation skills and effective communication 

Desired Qualifications:

• Clinical research expertise in relevant therapy area in study design, protocol development, monitoring and implementing clinical trials, interpreting and reporting trial results 

• Credibility in scientific and commercial environments

The annual base pay for this position ranges from $241,613 – $362,420 USD. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. 

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility.

Join us in our unique and bold world. 

Date Posted

26-Oct-2026

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.