Executive Director, Global Commercial Lead, HCC

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.

General Description:

BeOne’s Solid Tumor organization has committed to advancing novel therapies across 3 core franchises:  Breast/Gynecological, Gastrointestinal (GI), and Lung Cancers.  Having advanced more than 20 clinical candidates in the past 3 years within these franchises, the company will present proof-of-concept data on 5 assets before end-2026.  Within the GI franchise, BeOne presented at ASCO 2026 proof-of-concept data for our GPC3x41BB bispecific antibody in late line HCC patients.  BeOne has now formed a Global Product Team (GPT) to execute registration-intent studies for this molecule, and will soon be forming a corresponding Global Brand Teams (GBT) to deliver successful commercial launches around the globe.

This highly visible role will serve as the Global Commercial Lead (GCL) for this asset with responsibility to drive launch preparations and readiness across global functions and affiliate partners.  The person selected for this role will mobilize the first GBT for the GI franchise with team members representing different functions and markets.  Together, the GBT will create the first global brand plan for this asset that confirms the opportunity size, defines the commercial strategies to realize the opportunity, and identifies and leads implementation of the tactical plans to achieve successful commercial launches around the globe. 

The person selected for this role will need to be visionary and a recognized leader across the R&D and commercial interface.  He / she will collaborate closely with cross-functional teams to ensure alignment with business objectives and market needs across various functional disciplines and BeOne Regions. This role requires a deep understanding of drug development and commercialization processes, strong leadership capabilities, and a proven track record in working cross-functionally to lead matrix teams across the entirety of product launch and LCM planning. The role reports to the Vice President, Global Commercial Strategy & Operations (GCSO), Solid Tumors.

Essential Functions of the Job: 

• Provide strategic leadership for a highly visible asset within our Solid Tumor pipeline, developing the global commercial strategies for first launch, helping to shape the lifecycle management plan, serving as the commercial voice at the Global Product Team (GPT), and representing the Brand across BeOne territories, with senior leadership, and with external stakeholders.

• Lead the Global Brand Team (GBT) ensuring productive information exchange and best practice sharing between GPT, GBT, and regional / affiliate team members.  Develop an aligned view of brand growth drivers and ensure progress to plan consistent with agreed business objectives. 

• Represent ONE commercial voice to Global Product Team (GPT), R&D, Tech Ops, Executive Leadership, and Solid Tumor Franchise Teams to drive organizational alignment and progress.

• Lead key cross-functional processes including the Annual Brand Plan, the Annual Operating Plan (AOP), and the Long-Range Plan (LRP) processes.

• Build, inspire, and develop talent within the global commercial team as BeOne resources the brand teams through launch preparations and commercialization.

• Collaborate with cross-regional and cross-functional team members to shape brand strategies for multiple indications to form an integrated view of lifecycle management priorities.

• Integrate major market input into global launch readiness plans and support the implementation / execution of global commercial strategies in local markets.

• Ensure long-term growth by translating complex clinical evidence into a unified global narrative that drives market leadership.

• Consolidate competitor understanding that spans multiple modalities and indications into a cohesive product view.  Develop succinct competitive response plans that are grounded in a deep understanding of marketplace performance and competitor strategies.

• Collaborate with functional leads to ensure insight generation that helps drive business performance, and develop and maintain a Global Brand Dashboard.

• Lead the cross-functional team to execute launch readiness preparations and discussions with GBT member markets.

• Drive value maximization and recommend growth strategies to meet long-term Solid Tumor portfolio ambitions.

• Collaborate with Medical Affairs, Regions, and Corporate Communications to craft and refine stakeholder communications.

• Partner with Tech Ops to ensure optimized supply and demand management.

• Maintain strong relationships with both internal colleagues and external customers and thought leaders to address market opportunities.

Minimum Requirements/Qualifications:

• 12+ years of experience in pharmaceutical marketing/healthcare-related commercial experience, inclusive of 5+ years in oncology/hematology.

• 5+ years of Global Marketing/New Product Planning experience.

• Demonstrated experience in leading brand strategy/new product planning at various stages of the product lifecycle.

• Product launch experience, either from a Global-based role or Market-based role

• Advanced or expert competency in solid tumors and highly competitive markets

• Strong team player who can incorporate input from key stakeholders (both internally and externally) and drive cross-regional and cross-functional alignment.

• Proven ability to inspire, motivate and lead high-performing, matrixed teams.

• Highly-skilled and effective in engaging, connecting, and influencing across all levels from senior leadership to local marketing teams.

• Understanding of change management principles and experience driving change across an organization.

• Strong ability and desire to work across time zones, geographies, and cultures to improve the lives of patients and caregivers.

• Education:  Bachelor’s Degree in Marketing, Sciences, or a related field

Preferred Qualifications:

• 15+ years of experience in pharmaceutical marketing/healthcare-related commercial experience, inclusive of 5+ years in Global Marketing/New Product Planning for oncology/hematology.

• Demonstrated understanding in the reimbursement considerations for medicines across the major markets (US/EU5/Japan/China)

• In-country experience in a major market (US/EU5/Japan/China)

• Previous international assignments

• Education:  Master’s Degree in Business (MBA) or PhD

Global Competencies

When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.

• Fosters Teamwork
• Provides and Solicits Honest and Actionable Feedback
• Self-Awareness
• Acts Inclusively
• Demonstrates Initiative
• Entrepreneurial Mindset
• Continuous Learning
• Embraces Change
• Results-Oriented
• Analytical Thinking/Data Analysis
• Financial Excellence
• Communicates with Clarity

Salary Range: $269,400.00 - $349,400.00 annually

BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process.  Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness.

We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com.