Director, Registry Operations

<span style="font-size:11pt;"><span style="line-height:normal;"><span><span style="font-family:Aptos, sans-serif;"><b><span style="font-family:Calibri, sans-serif;">Company Overview </span></b></span></span></span></span><br><span style="font-size:11pt;"><span style="line-height:normal;"><span><span style="font-family:Aptos, sans-serif;"><span style="font-family:Calibri, sans-serif;">Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients and their families living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases and provide meaningful support for healthcare providers and patients and their families. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to learn, adapt, and our tenacity to overcome barriers, together.</span></span></span></span></span><br><br><span style="font-size:11pt;"><span style="line-height:normal;"><span style="font-family:Aptos, sans-serif;"><b><span style="font-family:Calibri, sans-serif;">Opportunity Overview</span></b></span></span></span><br><span style="font-size:11pt;"><span style="line-height:normal;"><span style="font-family:Aptos, sans-serif;"><span style="font-family:Calibri, sans-serif;">The Director, Registry Operations will oversee the development and implementation of registers for Bardet Biedl Syndrome (BBS) and Hypothalamic Obesity (HO), ensuring their strategic design, operational efficiency and long term sustainability. This role requires strong project management skills, cross-functional collaboration acumen, and expertise in healthcare data governance. The Director, Registry Operations will work closely with internal stakeholders, external vendors, regulatory bodies, and external experts to create and maintain robust registers that will support clinical insights, evidence generation, research initiatives and publication plans.</span></span></span></span><br><br><span style="font-size:11pt;"><span style="line-height:normal;"><span style="font-family:Aptos, sans-serif;"><b><span style="font-family:Calibri, sans-serif;">Responsibilities and Duties</span></b></span></span></span><ul><li style="margin-left:8px;"><span style="font-size:12pt;"><span style="font-family:'Times New Roman', serif;"><span style="font-size:11pt;"><span style="font-family:Calibri, sans-serif;">Establish and implement the governance structure for the registers, ensuring compliance with all relevant legal and regulatory frameworks.</span></span></span></span></li><li style="margin-left:8px;"><span style="font-size:12pt;"><span style="font-family:'Times New Roman', serif;"><span style="font-size:11pt;"><span style="font-family:Calibri, sans-serif;">Work in close collaboration with the Legal team to guarantee alignment with national and international legislations.</span></span></span></span></li><li style="margin-left:8px;"><span style="font-size:12pt;"><span style="font-family:'Times New Roman', serif;"><span style="font-size:11pt;"><span style="font-family:Calibri, sans-serif;">Define success metrics and oversee the register's long-term strategic direction.</span></span></span></span></li><li style="margin-left:8px;"><span style="font-size:12pt;"><span style="font-family:'Times New Roman', serif;"><span style="font-size:11pt;"><span style="font-family:Calibri, sans-serif;">Lead discussions with external experts (EEs), Medical, and Market Access teams to design optimal Case Report Forms (CRFs) tailored to disease indications.</span></span></span></span></li><li style="margin-left:8px;"><span style="font-size:12pt;"><span style="font-family:'Times New Roman', serif;"><span style="font-size:11pt;"><span style="font-family:Calibri, sans-serif;">Partner with the selected vendor to build a secure, scalable, and user-friendly register platform that meets industry standards.</span></span></span></span></li><li style="margin-left:8px;"><span style="font-size:12pt;"><span style="font-family:'Times New Roman', serif;"><span style="font-size:11pt;"><span style="font-family:Calibri, sans-serif;">Conduct regular audits of platform functionality, ensuring data integrity and seamless integration with relevant systems.</span></span></span></span></li><li style="margin-left:8px;"><span style="font-size:12pt;"><span style="font-family:'Times New Roman', serif;"><span style="font-size:11pt;"><span style="font-family:Calibri, sans-serif;">Lead and coordinate meetings with internal and external stakeholders involved in the project.</span></span></span></span></li><li style="margin-left:8px;"><span style="font-size:12pt;"><span style="font-family:'Times New Roman', serif;"><span style="font-size:11pt;"><span style="font-family:Calibri, sans-serif;">Provide ongoing support to the Operational Committee in managing the day-to-day operations of the registers.</span></span></span></span></li><li style="margin-left:8px;"><span style="font-size:12pt;"><span style="font-family:'Times New Roman', serif;"><span style="font-size:11pt;"><span style="font-family:Calibri, sans-serif;">Assist in setting up local registries that will contribute to the registers.</span></span></span></span></li><li style="margin-left:8px;"><span style="font-size:12pt;"><span style="font-family:'Times New Roman', serif;"><span style="font-size:11pt;"><span style="font-family:Calibri, sans-serif;">Monitor data entry, integrity, and analytics to ensure accuracy and reliability.</span></span></span></span></li><li style="margin-left:8px;"><span style="font-size:12pt;"><span style="font-family:'Times New Roman', serif;"><span style="font-size:11pt;"><span style="font-family:Calibri, sans-serif;">Support the development of a three-year publication plan, ensuring key findings from the registers contribute to scientific literature and healthcare advancements.</span></span></span></span></li><li style="margin-left:8px;"><span style="font-size:12pt;"><span style="font-family:'Times New Roman', serif;"><span style="font-size:11pt;"><span style="font-family:Calibri, sans-serif;">Collaborate with research teams to develop insights and drive evidence generation initiatives.</span></span></span></span></li></ul><br><span style="font-size:11pt;"><span style="line-height:normal;"><span style="font-family:Aptos, sans-serif;"><b><span style="font-family:Calibri, sans-serif;">Qualifications and Skills</span></b></span></span></span><ul><li style="text-align:justify;margin-left:8px;"><span style="font-size:11pt;"><span style="line-height:normal;"><span style="font-family:Aptos, sans-serif;"><span style="font-family:Calibri, sans-serif;">Bachelor's degree in Public Health, Business Administration, Science, or a related field</span></span></span></span></li><li style="text-align:justify;margin-left:8px;"><span style="font-size:11pt;"><span style="line-height:normal;"><span style="font-family:Aptos, sans-serif;"><span style="font-family:Calibri, sans-serif;">Minimum of 10 years of relevant experience</span></span></span></span></li><li style="text-align:justify;margin-left:8px;"><span style="font-size:11pt;"><span style="line-height:normal;"><span style="font-family:Aptos, sans-serif;"><span style="font-family:Calibri, sans-serif;">Strong background in clinical registries, healthcare databases, or real-world evidence projects.</span></span></span></span></li><li style="text-align:justify;margin-left:8px;"><span style="font-size:11pt;"><span style="line-height:normal;"><span style="font-family:Aptos, sans-serif;"><span style="font-family:Calibri, sans-serif;">Experience in regulatory and legal aspects of healthcare data management.</span></span></span></span></li><li style="text-align:justify;margin-left:8px;"><span style="font-size:11pt;"><span style="line-height:normal;"><span style="font-family:Aptos, sans-serif;"><span style="font-family:Calibri, sans-serif;">Proven track record of managing external vendors and technology implementation.</span></span></span></span></li><li style="text-align:justify;margin-left:8px;"><span style="font-size:11pt;"><span style="line-height:normal;"><span style="font-family:Aptos, sans-serif;"><span style="font-family:Calibri, sans-serif;">Excellent communication, stakeholder management, and leadership skills.</span></span></span></span></li><li style="text-align:justify;margin-left:8px;"><span style="font-size:11pt;"><span style="line-height:normal;"><span style="font-family:Aptos, sans-serif;"><span style="font-family:Calibri, sans-serif;">Familiarity with clinical research methodologies</span></span></span></span></li><li style="text-align:justify;margin-left:8px;"><span style="font-size:11pt;"><span style="line-height:normal;"><span style="font-family:Aptos, sans-serif;"><span style="font-family:Calibri, sans-serif;">Fluent in English</span></span></span></span></li></ul><div style="text-align:justify;margin-left:8px;"><br><span style="font-size:12px;"><em><span style="line-height:normal;"><span style="font-family:Aptos, sans-serif;"><span style="font-family:Calibri, sans-serif;">More about Rhythm</span></span></span></em></span>