Join us as we transform immunology and deliver medicines that help autoimmune patients get their lives back. argenx is preparing for multi-dimensional expansion to reach more patients through a rich pipeline of differentiated assets, led by VYVGART, our first-in-class neonatal Fc receptor blocker approved for the treatment of gMG, and with the potential to treat patients across dozens of severe autoimmune diseases.

We are building a new kind of biotech company, one that maintains its roots as a science-based start-up and pushes our commitment to innovate across all corners of our business. We strive to inspire and grow our company, our partnerships, our science, and our people, because when we do, we deliver more for patients. 

Position purpose

Adimanebart (ARGX-119) is a novel anti-MuSK (muscle-specific kinase) agonist monoclonal antibody being developed as a pipeline in a product for neuromuscular diseases. argenx is seeking a dynamic clinical development leader to provide expertise across multiple indications, including CMS (congenital myasthenic syndromes), ALS (amyotrophic lateral sclerosis), and SMA (spinal muscular atrophy) clinical programs, while also driving the rapid evaluation of new indications. The candidate will be responsible for delivering strategic clinical development leadership and oversight as part of the Asset Strategy Team (a cross-functional group focused on maximizing asset potential), working closely with other team members and the indication development teams to maximize the value of the asset and the success of the multi-indication program. The ideal candidate will have significant experience in clinical development for neurologic disorders and a proven track record in drug development.

Key Accountabilities/Responsibilities:

Deliver strategic clinical development planning and insight for the asset across all stages, including TPP, indication selection, labelling, and assessment of efficacy, safety, and competitor data. Oversee and guide the clinical development physicians, setting standards, coaching, and identifying high performers. Enhance external client satisfaction through strong collaboration with academic medical centers, positioning argenx as a partner of choice and ensuring valuable scientific input. Support internal clients by closely working with senior management and function heads, anticipating needs and ensuring clinical development excellence. Foster cross-functional collaboration on policies and training to streamline procedures and improve efficiency; ensure quality clinical development partnerships. Build and sustain a top-tier clinical development physician team.

Desired Skills and Experience:

• Medical Doctor; neurology specialty education required having acquired  in-depth understanding of global drug development , registration and commercialization process based on relevant experience of at least 7 years in the pharma/biotech industry.

• Excellent English, both written and spoken is a must, as well as ability to travel.

• Proven leadership, motivational and interpersonal skills in a global and intercultural environment, including leading through influence (without having direct reporting lines).  

• Pro-active problem solver with negotiation skills.

• Must provide clear vision, direction, and purpose for  the different development teams, remaining sensitive to the different cultural needs in a global organisation.

• Strong communication skills to ensure that project plans and status are transparent, and that risks, issues, and results are clear to all involved parties.  A matrix structure requires additional skills in gathering decision information, negotiation and communicating decisions and action.

• Executes his/her responsibilities with knowledge, accuracy, persistence, resilience and creativity, being an accomplished team player whilst maintaining medical integrity.

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For applicants in the United States: The annual base salary hiring range for this position is $296,000.00 - $407,000.00 USD. This range reflects our good faith estimate at the time of posting. Individual compensation is determined using objective, inclusive, and job-related criteria such as relevant experience, skills, demonstrated competencies and internal equity. This means actual pay may differ from the posted range when justified by these factors. Because market conditions evolve, pay ranges are reviewed regularly and may be adjusted to remain aligned with external benchmarks.

This job is eligible to participate in our short-term and long-term incentive programs, subject to the terms and conditions of those plans and applicable policies. It also includes a comprehensive benefits package, including but not limited to retirement savings plans, health benefits and other benefits subject to the terms of the applicable plans and program guidelines.

At argenx, all applicants are welcomed in an inclusive environment. They will receive equal consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other applicable legally protected characteristics. argenx is proud to be an equal opportunity employer.

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If you require reasonable accommodation in completing your application, interviewing, or otherwise participating in the candidate selection process please contact us at hr.us@argenx.com. Only inquiries related to an accommodation request will receive a response.