Ventricular Fibrillation

2
Pipeline Programs
4
Companies
7
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
2
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Biotronik
BiotronikGermany - Berlin
4 programs
2
ICD or CRT-D with Home Monitoring feature deactivatedPhase 41 trial
Implantable Cardioverter DefibrillatorPhase 41 trial
Home Monitoring provided by Biotronik ICD and CRT-D devicesN/A1 trial
SD01 ICD leadN/A1 trial
Active Trials
NCT00776087Terminated409Est. Oct 2016
NCT02014675Completed280Est. Sep 2024
NCT00538356Completed720Est. Aug 2013
+1 more trials
Heidelberg Pharma
Heidelberg PharmaGermany - Ladenburg
1 program
EEGN/A1 trial
Active Trials
NCT00176176Unknown30
Rhythm Pharmaceuticals
1 program
Left Ventricular Capture Management StudyN/A1 trial
Active Trials
NCT01089634Completed151Est. Dec 2010
PEEL Therapeutics
PEEL TherapeuticsUT - Salt Lake City
1 program
Vector change defibrillationN/A1 trial
Active Trials
NCT03249948CompletedEst. Mar 2020

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
BiotronikICD or CRT-D with Home Monitoring feature deactivated
BiotronikImplantable Cardioverter Defibrillator
PEEL TherapeuticsVector change defibrillation
BiotronikSD01 ICD lead
BiotronikHome Monitoring provided by Biotronik ICD and CRT-D devices
Rhythm PharmaceuticalsLeft Ventricular Capture Management Study

Clinical Trials (7)

Total enrollment: 1,745 patients across 7 trials

NCT00538356BiotronikICD or CRT-D with Home Monitoring feature deactivated

Influence of Home Monitoring on the Clinical Status of Heart Failure Patients With an Impaired Left Ventricular Function

Start: Jul 2007Est. completion: Aug 2013720 patients
Phase 4Completed
NCT00401466BiotronikImplantable Cardioverter Defibrillator

Remote Follow-up of Patients Receiving Implantable Cardioverter Defibrillator for Prophylactic Therapy

Start: Jan 2004Est. completion: Jul 2008155 patients
Phase 4Completed
NCT00176176Heidelberg PharmaEEG

Investigation of Cognitive Function Before and After Induced Ventricular Fibrillation in Electrophysiological (EP) Study

30 patients
N/AUnknown
NCT03249948PEEL TherapeuticsVector change defibrillation

DOuble SEquential External Defibrillation for Refractory VF Pilot Study

Start: Mar 2018Est. completion: Mar 2020
N/ACompleted
NCT02014675BiotronikSD01 ICD lead

SD01 Registry (SD01 ICD Lead)

Start: Mar 2014Est. completion: Sep 2024280 patients
N/ACompleted
NCT00776087BiotronikHome Monitoring provided by Biotronik ICD and CRT-D devices

European Health Economic Trial on Home Monitoring in ICD and CRT-D Patients (EuroEco)

Start: Oct 2008Est. completion: Oct 2016409 patients
N/ATerminated
NCT01089634Rhythm PharmaceuticalsLeft Ventricular Capture Management Study

Left Ventricular Capture Management Study

Start: Oct 2007Est. completion: Dec 2010151 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

4 companies competing in this space