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Trauma Injury

3
Pipeline Programs
9
Companies
9
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
2
0
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

9 companies ranked by most advanced pipeline stage

Bryan Corporation
Bryan CorporationOH - Cincinnati
2 programs
1
1
CryoprecipitatePhase 31 trial
Thrombate infusionPhase 2
Active Trials
NCT04704869Completed1,604Est. Nov 2022
Oregon Therapeutics
Oregon TherapeuticsFrance - Paris
1 program
1
Prothrombin Complex Concentrate, HumanPhase 21 trial
Active Trials
NCT04019015Unknown166Est. Mar 2025
Innovation Pharmaceuticals
1 program
Bleeding Control BasicN/A1 trial
Active Trials
NCT03538379Unknown34Est. Jul 2018
Labcorp
LabcorpBURLINGTON, NC
1 program
Captain Sonar ExpositionN/A1 trial
Active Trials
NCT05628519Completed100Est. Feb 2022
Human BioSciences
Human BioSciencesWV - Martinsburg
1 program
Caregivers' Aid to Accelerate Recovery after pediatric EmergenciesN/A1 trial
Active Trials
NCT04579198Completed54Est. Dec 2024
Merit Medical
Merit MedicalSOUTH JORDAN, UT
1 program
Micro Plug SetN/A1 trial
Active Trials
NCT04218292Unknown40Est. Feb 2022
Arrowhead Pharmaceuticals
1 program
Packed Red Blood Cell AdministrationN/A1 trial
Active Trials
NCT06402669Completed20,000Est. Jan 2024
Mission Therapeutics
Mission TherapeuticsUK - Cambridge
1 program
Predictive Accuracy of PLR and PNR in Detecting ETICN/A1 trial
Active Trials
NCT07046858Recruiting250Est. Nov 2025
Grifols
GrifolsNEW YORK, NY
1 program
Thrombate infusionPHASE_21 trial
Active Trials
NCT05794165Enrolling By Invitation314Est. Mar 2027

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
Bryan CorporationCryoprecipitate
GrifolsThrombate infusion
Oregon TherapeuticsProthrombin Complex Concentrate, Human
Mission TherapeuticsPredictive Accuracy of PLR and PNR in Detecting ETIC
Human BioSciencesCaregivers' Aid to Accelerate Recovery after pediatric Emergencies
Arrowhead PharmaceuticalsPacked Red Blood Cell Administration
LabcorpCaptain Sonar Exposition
Merit MedicalMicro Plug Set
Innovation PharmaceuticalsBleeding Control Basic

Clinical Trials (9)

Total enrollment: 22,562 patients across 9 trials

NCT04704869Bryan CorporationCryoprecipitate

Early Use of Cryoprecipitate With Major Hemorrhage Protocol (MHP) Activation

Start: Jan 2017Est. completion: Nov 20221,604 patients
Phase 3Completed
NCT05794165GrifolsThrombate infusion

Antithrombin to Improve Thromboprophylaxis and Reduce the Incidence of Trauma-Related Venous Thromboembolism

Start: Sep 2023Est. completion: Mar 2027314 patients
Phase 2Enrolling By Invitation
NCT04019015Oregon TherapeuticsProthrombin Complex Concentrate, Human

Prehospital Kcentra for Hemorrhagic Shock

Start: Mar 2021Est. completion: Mar 2025166 patients
Phase 2Unknown
NCT07046858Mission TherapeuticsPredictive Accuracy of PLR and PNR in Detecting ETIC

Predictive Accuracy of PLR and PNR in Detecting ETIC

Start: Oct 2023Est. completion: Nov 2025250 patients
N/ARecruiting
NCT04579198Human BioSciencesCaregivers' Aid to Accelerate Recovery after pediatric Emergencies

Using mHealth to Improve Emotional Recovery After Pediatric Injury

Start: Mar 2022Est. completion: Dec 202454 patients
N/ACompleted
NCT06402669Arrowhead PharmaceuticalsPacked Red Blood Cell Administration

Extremity Trauma At a Level 1 Trauma Center

Start: Jan 2022Est. completion: Jan 202420,000 patients
N/ACompleted
NCT05628519LabcorpCaptain Sonar Exposition

Captain Sonar Impact on Trauma Patient Management

Start: Sep 2021Est. completion: Feb 2022100 patients
N/ACompleted
NCT04218292Merit MedicalMicro Plug Set

Micro Plug Set - Post Market Clinical Follow-up (PMCF) Plan

Start: Mar 2020Est. completion: Feb 202240 patients
N/AUnknown
NCT03538379Innovation PharmaceuticalsBleeding Control Basic

Tourniquet Training Effectiveness Study

Start: Apr 2018Est. completion: Jul 201834 patients
N/AUnknown

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs, potential near-term approvals
1 actively recruiting trials targeting 22,562 patients
9 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.