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Tonsillectomy

7
Pipeline Programs
7
Companies
8
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
4
2
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
2100%
+ 9 programs with unclassified modality

Competitive Landscape

7 companies ranked by most advanced pipeline stage

MSD
MSDIreland - Ballydine
2 programs
1
1
RocuroniumPhase 41 trial
Administration of placeboPhase 31 trial
Active Trials
NCT00756873Unknown90Est. Dec 2009
NCT06225466Completed172Est. Sep 2024
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
2 programs
1
1
RocuroniumPhase 4
Administration of placeboPhase 3
Pfizer
PfizerNEW YORK, NY
2 programs
1
1
DexmedetomidinePhase 31 trial
CelecoxibPhase 2Small Molecule1 trial
Active Trials
NCT02934191Completed172Est. Jan 2019
NCT01528891Completed418Est. Aug 2014
Cumberland Pharmaceuticals
1 program
1
Intravenous ibuprofenPhase 3Small Molecule1 trial
Active Trials
NCT01332253Completed161Est. Aug 2012
Medtronic
MedtronicNJ - Phillipsburg
2 programs
A bipolar instrument for tonsillectomiesN/A1 trial
BiZact™: A bipolar instrument for tonsillectomiesN/A1 trial
Active Trials
NCT02876575Completed48Est. Oct 2018
NCT03266094Completed60Est. Jul 2019
UNION therapeutics
UNION therapeuticsDenmark - Hellerup
1 program
The CMCPCTH Research in Chinese ChildrenN/A1 trial
Active Trials
NCT05206799Unknown25,000Est. Feb 2024
City Therapeutics
City TherapeuticsMA - Cambridge
1 program
The CMCPCTH Research in Chinese ChildrenN/A

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
MSDRocuronium
PfizerDexmedetomidine
Cumberland PharmaceuticalsIntravenous ibuprofen
MSDAdministration of placebo
PfizerCelecoxib
UNION therapeuticsThe CMCPCTH Research in Chinese Children
MedtronicBiZact™: A bipolar instrument for tonsillectomies
MedtronicA bipolar instrument for tonsillectomies

Clinical Trials (8)

Total enrollment: 26,121 patients across 8 trials

NCT06225466MSDRocuronium

Muscle Relaxation for Pediatric Adenotonsillectomy

Start: Apr 2024Est. completion: Sep 2024172 patients
Phase 4Completed
NCT01528891PfizerDexmedetomidine

Dexmedetomidine as a Rapid Bolus in Children for Emergence Agitation

Start: Jan 2012Est. completion: Aug 2014418 patients
Phase 3Completed
NCT01332253Cumberland PharmaceuticalsIntravenous ibuprofen

Safety and Efficacy of Intravenous Ibuprofen for Treatment of Pain in Pediatric Patients Undergoing Tonsillectomy

Start: Jul 2011Est. completion: Aug 2012161 patients
Phase 3Completed
NCT00756873MSDAdministration of placebo

Etoricoxib in Ear Nose Throat Surgery

Start: Oct 2008Est. completion: Dec 200990 patients
Phase 3Unknown
NCT02934191PfizerCelecoxib

Celecoxib After Tonsillectomy

Start: Jun 2016Est. completion: Jan 2019172 patients
Phase 2Completed
NCT05206799UNION therapeuticsThe CMCPCTH Research in Chinese Children

The CMCPCTH Research in Chinese Children

Start: Jan 2022Est. completion: Feb 202425,000 patients
N/AUnknown
NCT03266094MedtronicBiZact™: A bipolar instrument for tonsillectomies

A Study of BiZact™ on Children and Adolescents Undergoing Tonsillectomy

Start: Sep 2018Est. completion: Jul 201960 patients
N/ACompleted
NCT02876575MedtronicA bipolar instrument for tonsillectomies

A Study of BiZact™ on Adults Undergoing Tonsillectomy

Start: Feb 2017Est. completion: Oct 201848 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

4 late-stage (Phase 3) programs, potential near-term approvals
7 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.