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Tonsillectomy

7
Pipeline Programs
7
Companies
6
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
4
2
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
2100%
+ 9 programs with unclassified modality

Competitive Landscape

7 companies ranked by most advanced pipeline stage

MSD
MSDIreland - Ballydine
2 programs
1
1
RocuroniumPhase 4
Administration of placeboPhase 3
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
2 programs
1
1
RocuroniumPhase 4
Administration of placeboPhase 3
Pfizer
PfizerNEW YORK, NY
2 programs
1
1
DexmedetomidinePhase 31 trial
CelecoxibPhase 2Small Molecule1 trial
Active Trials
NCT02934191Completed172Est. Jan 2019
NCT01528891Completed418Est. Aug 2014
Cumberland Pharmaceuticals
1 program
1
Intravenous ibuprofenPhase 3Small Molecule1 trial
Active Trials
NCT01332253Completed161Est. Aug 2012
Medtronic
MedtronicNJ - Phillipsburg
2 programs
A bipolar instrument for tonsillectomiesN/A1 trial
BiZact™: A bipolar instrument for tonsillectomiesN/A1 trial
Active Trials
NCT02876575Completed48Est. Oct 2018
NCT03266094Completed60Est. Jul 2019
City Therapeutics
City TherapeuticsMA - Cambridge
1 program
The CMCPCTH Research in Chinese ChildrenN/A
UNION therapeutics
UNION therapeuticsDenmark - Hellerup
1 program
The CMCPCTH Research in Chinese ChildrenN/A1 trial
Active Trials
NCT05206799Unknown25,000Est. Feb 2024

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
PfizerDexmedetomidine
Cumberland PharmaceuticalsIntravenous ibuprofen
PfizerCelecoxib
UNION therapeuticsThe CMCPCTH Research in Chinese Children
MedtronicBiZact™: A bipolar instrument for tonsillectomies
MedtronicA bipolar instrument for tonsillectomies

Clinical Trials (6)

Total enrollment: 25,859 patients across 6 trials

NCT01528891PfizerDexmedetomidine

Dexmedetomidine as a Rapid Bolus in Children for Emergence Agitation

Start: Jan 2012Est. completion: Aug 2014418 patients
Phase 3Completed
NCT01332253Cumberland PharmaceuticalsIntravenous ibuprofen

Safety and Efficacy of Intravenous Ibuprofen for Treatment of Pain in Pediatric Patients Undergoing Tonsillectomy

Start: Jul 2011Est. completion: Aug 2012161 patients
Phase 3Completed
NCT02934191PfizerCelecoxib

Celecoxib After Tonsillectomy

Start: Jun 2016Est. completion: Jan 2019172 patients
Phase 2Completed
NCT05206799UNION therapeuticsThe CMCPCTH Research in Chinese Children

The CMCPCTH Research in Chinese Children

Start: Jan 2022Est. completion: Feb 202425,000 patients
N/AUnknown
NCT03266094MedtronicBiZact™: A bipolar instrument for tonsillectomies

A Study of BiZact™ on Children and Adolescents Undergoing Tonsillectomy

Start: Sep 2018Est. completion: Jul 201960 patients
N/ACompleted
NCT02876575MedtronicA bipolar instrument for tonsillectomies

A Study of BiZact™ on Adults Undergoing Tonsillectomy

Start: Feb 2017Est. completion: Oct 201848 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

4 late-stage (Phase 3) programs, potential near-term approvals
7 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.