Spinal Cord Injury

7
Pipeline Programs
13
Companies
15
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
4
2
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

13 companies ranked by most advanced pipeline stage

Sanofi
SanofiPARIS, France
1 program
1
HP184Phase 21 trial
Active Trials
NCT00093275Completed262Est. Dec 2005
VP
1 program
1
CethrinPhase 1/21 trial
Active Trials
NCT00500812Completed48Est. Feb 2009
BioArctic
BioArcticSweden - Stockholm
1 program
1
SC0806 and rehabilitationPhase 1/21 trial
Active Trials
NCT02490501CompletedEst. May 2025
C
ColoplastAustralia - Mulgrave
2 programs
1
Intermittent catheterisationPhase 11 trial
Intermittent catheter CP063CCN/A1 trial
Active Trials
NCT01142115CompletedEst. May 2010
NCT01292941WithdrawnEst. Jun 2011
Lineage Cell Therapeutics
1 program
1
GRNOPC1Phase 11 trial
Active Trials
NCT01217008CompletedEst. Jul 2013
NervGen Pharma
NervGen PharmaVANCOUVER, British Columbia, Canada
1 program
1
NVG-291Phase 11 trial
Active Trials
NCT05308953CompletedEst. Jul 2023
Knight Therapeutics
Knight TherapeuticsQC - Montréal
1 program
1
bone marrow progenitor cellsPhase 11 trial
Active Trials
NCT01328860Terminated10Est. Jun 2016
Ekso Bionics
Ekso BionicsSAN RAFAEL, CA
2 programs
EksoN/A1 trial
Overground Robotic ExoskeletonN/A1 trial
Active Trials
NCT02132702CompletedEst. Jan 2017
NCT07030322Enrolling By InvitationEst. Sep 2027
Alliance Pharmaceuticals
2 programs
Gut Dysbiosis in Spinal Cord Injury RehabilitationN/A1 trial
Molecular Determinants of Spinal Cord Injury RehabilitationN/A1 trial
Active Trials
NCT06892106Completed106Est. Oct 2023
NCT07383077Completed106Est. Oct 2023
AT
Amarna TherapeuticsNetherlands - Leiden
1 program
Bone Marrow Collection in Healthy Volunteers (iCell)N/A
N
NeuroplastFrance - Montpellier
1 program
Bone Marrow Collection in Healthy Volunteers (iCell)N/A1 trial
Active Trials
NCT02118740Unknown15Est. Apr 2018
Synapse Biomedical
Synapse BiomedicalOH - Oberlin
1 program
NeuRx DPSN/A1 trial
Active Trials
NCT00010374CompletedEst. Oct 2008
T-Therapeutics
T-TherapeuticsUK - Cambridge
1 program
escitalopram oxalateN/A1 trial
Active Trials
NCT01538693CompletedEst. May 2015

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
SanofiHP184
BioArcticSC0806 and rehabilitation
Vertex PharmaceuticalsCethrin
NervGen PharmaNVG-291
Knight Therapeuticsbone marrow progenitor cells
ColoplastIntermittent catheterisation
Lineage Cell TherapeuticsGRNOPC1
Ekso BionicsOverground Robotic Exoskeleton
Alliance PharmaceuticalsMolecular Determinants of Spinal Cord Injury Rehabilitation
Alliance PharmaceuticalsGut Dysbiosis in Spinal Cord Injury Rehabilitation
NeuroplastBone Marrow Collection in Healthy Volunteers (iCell)
Ekso BionicsEkso
T-Therapeuticsescitalopram oxalate
ColoplastIntermittent catheter CP063CC
Synapse BiomedicalNeuRx DPS

Clinical Trials (15)

Total enrollment: 547 patients across 15 trials

NCT00093275SanofiHP184

HP184 in Chronic Spinal Cord Injury Subjects

Start: Oct 2004Est. completion: Dec 2005262 patients
Phase 2Completed
NCT02490501BioArcticSC0806 and rehabilitation

Safety and Efficacy of SC0806 (Fibroblast Growth Factor 1 and a Device) in Traumatic Spinal Cord Injury Subjects

Start: Jun 2015Est. completion: May 2025
Phase 1/2Completed
NCT00500812Vertex PharmaceuticalsCethrin

A Safety Study for Cethrin (BA-210) in the Treatment of Acute Thoracic and Cervical Spinal Cord Injuries

Start: Feb 2005Est. completion: Feb 200948 patients
Phase 1/2Completed
NCT05308953NervGen PharmaNVG-291

A Phase I Safety Study of NVG-291 in Healthy Adults

Start: May 2021Est. completion: Jul 2023
Phase 1Completed
NCT01328860Knight Therapeuticsbone marrow progenitor cells

Autologous Stem Cells for Spinal Cord Injury (SCI) in Children

Start: Apr 2011Est. completion: Jun 201610 patients
Phase 1Terminated
NCT01292941ColoplastIntermittent catheterisation

Clinical Study Evaluating Safety of a New Catheter for Urinary Intermittent Catheter in Healthy Volunteers

Start: Mar 2011Est. completion: Jun 2011
Phase 1Withdrawn
NCT01217008Lineage Cell TherapeuticsGRNOPC1

Safety Study of GRNOPC1 in Spinal Cord Injury

Start: Oct 2010Est. completion: Jul 2013
Phase 1Completed
NCT07030322Ekso BionicsOverground Robotic Exoskeleton

Health and Financial Impact on the Use of a Personal Exoskeleton in the Home and Community: a Case Study

Start: Aug 2025Est. completion: Sep 2027
N/AEnrolling By Invitation
NCT07383077Alliance PharmaceuticalsMolecular Determinants of Spinal Cord Injury Rehabilitation

Molecular Determinants of Spinal Cord Injury Rehabilitation

Start: May 2021Est. completion: Oct 2023106 patients
N/ACompleted
NCT06892106Alliance PharmaceuticalsGut Dysbiosis in Spinal Cord Injury Rehabilitation

Gut Dysbiosis in Spinal Cord Injury Rehabilitation

Start: May 2021Est. completion: Oct 2023106 patients
N/ACompleted
NCT02118740NeuroplastBone Marrow Collection in Healthy Volunteers (iCell)

Bone Marrow Collection in Healthy Volunteers (iCell)

Start: Jun 2015Est. completion: Apr 201815 patients
N/AUnknown
NCT02132702Ekso BionicsEkso

Performance Attributes and User Progression While Using Ekso

Start: Aug 2014Est. completion: Jan 2017
N/ACompleted
NCT01538693T-Therapeuticsescitalopram oxalate

Molecular Markers of Neuroplasticity During Exercise in People With Incomplete Spinal Cord Injury

Start: Dec 2011Est. completion: May 2015
N/ACompleted
NCT01142115ColoplastIntermittent catheter CP063CC

Test of Discomfort and Malaise of Two Different Urine Catheters in Healthy Volunteers

Start: Jan 2010Est. completion: May 2010
N/ACompleted
NCT00010374Synapse BiomedicalNeuRx DPS

Electrical Activation of The Diaphragm for Ventilatory Assist

Start: Feb 2000Est. completion: Oct 2008
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

13 companies competing in this space