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Sciatica

3
Pipeline Programs
6
Companies
6
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
1
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Medtronic
MedtronicNJ - Phillipsburg
2 programs
1
1
DIAM™ Spinal Stabilization SystemPhase 41 trial
MDT-15Phase 21 trial
Active Trials
NCT01917825Completed54Est. Oct 2016
NCT00749996Completed165Est. Jun 2013
Utah Medical
Utah MedicalIreland - Dublin
1 program
1
Physical therapy rehabilitationPhase 31 trial
Active Trials
NCT00942227Completed120Est. Dec 2012
Mission Therapeutics
Mission TherapeuticsUK - Cambridge
1 program
Pain Relief by Platelet-rich Plasma (PRP) TreatmentN/A1 trial
Active Trials
NCT01749839Unknown25Est. Dec 2014
Biogen
BiogenCAMBRIDGE, MA
1 program
BG00010PHASE_11 trial
Active Trials
NCT01405833Completed56Est. Sep 2012
Teva
TevaIsrael - Petach Tikva
1 program
CEP-37247PHASE_1_21 trial
Active Trials
NCT01240876Completed98Est. Apr 2013
Regeneron
RegeneronTARRYTOWN, NY
1 program
REGN475PHASE_2

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
MedtronicDIAM™ Spinal Stabilization System
Utah MedicalPhysical therapy rehabilitation
MedtronicMDT-15
TevaCEP-37247
BiogenBG00010
Mission TherapeuticsPain Relief by Platelet-rich Plasma (PRP) Treatment

Clinical Trials (6)

Total enrollment: 518 patients across 6 trials

NCT00749996MedtronicDIAM™ Spinal Stabilization System

Herniectomy Versus Herniectomy With a Spinal Stabilization System for the Treatment of Complex Disc Disease

Start: Nov 2006Est. completion: Jun 2013165 patients
Phase 4Completed
NCT00942227Utah MedicalPhysical therapy rehabilitation

The Value of Traction in Treatment of Lumbar Radiculopathy

Start: Jul 2009Est. completion: Dec 2012120 patients
Phase 3Completed
NCT01917825MedtronicMDT-15

A Study of the Pharmacokinetics, Safety, and Preliminary Efficacy of MDT-15 in Subjects With Lumbosacral Radiculopathy

Start: Jul 2013Est. completion: Oct 201654 patients
Phase 2Completed
NCT01240876TevaCEP-37247

Study to Evaluate the Safety and Efficacy of Placulumab (CEP-37247) Administered by the Transforaminal Epidural Route for the Treatment of Patients With Lumbosacral Radicular Pain Associated With Disk Herniation

Start: Jan 2011Est. completion: Apr 201398 patients
Phase 1/2Completed
NCT01405833BiogenBG00010

Study of the Safety, Tolerability, Pharmacokinetics and Safety of BG00010 (Neublastin) in Subjects With Sciatica.

Start: Jul 2011Est. completion: Sep 201256 patients
Phase 1Completed
NCT01749839Mission TherapeuticsPain Relief by Platelet-rich Plasma (PRP) Treatment

Pain Relief by Platelet-rich Plasma (PRP) Treatment

Start: Dec 2012Est. completion: Dec 201425 patients
N/AUnknown

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs, potential near-term approvals
6 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.