Pyruvate Kinase Deficiency

A Study to Provide Continued Access to Mitapivat for Participants Who Previously Completed an Agios-Sponsored Mitapivat Study

A Study Evaluating the Efficacy and Safety of AG-348 in Regularly Transfused Adult Participants With Pyruvate Kinase Deficiency (PKD)

Clinical Trial to Evaluate the Efficacy of Gene Therapy for Pyruvate Kinase Deficiency

A Study of Mitapivat in Participants With Sickle Cell Disease and Nephropathy

To Assess Safety of Mitapivat and Provide Proof of Concept of the Efficacy of the Drug in Patients With RBC Membranopathies or CDAII.

A Study of AG-348 in Adult Participants With Pyruvate Kinase (PK) Deficiency

Study of How Mitapivat Affects Midazolam Blood Levels in Healthy Participants

A Pharmacokinetic Study of Mitapivat in Participants With Moderate Hepatic Impairment Compared to Matched Healthy Control Participants With Normal Hepatic Function

A Study to Compare the Pharmacokinetics and Safety of Mitapivat 100 mg Tablet Formulation With Mitapivat 2 × 50 mg Tablet Formulation in Healthy Adult Participants

A Study to Assess the Relative Bioavailability and Effect of Food on the Coated Granule Formulation of Mitapivat in Healthy Participants

Gene Therapy for Pyruvate Kinase Deficiency (PKD)

Acquired Pyruvate Kinase Deficiency In Clonal Myeloid Neoplasms

Pyruvate Kinase (PK) Deficiency Global Longitudinal Registry: Patient-Reported Outcomes (PRO)

Pyruvate Kinase Deficiency Global Longitudinal Registry Substudy of Protocol AG348-C-008

Pyruvate Kinase Deficiency Epidemiological Study (PIECE)

Pyruvate Kinase Deficiency Global Longitudinal Registry

Pyruvate Kinase Deficiency Natural History Study