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Pre-Exposure Prophylaxis

3
Pipeline Programs
8
Companies
11
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
3
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

7 companies ranked by most advanced pipeline stage

Human BioSciences
Human BioSciencesWV - Martinsburg
5 programs
2
Daily oral PrEPPhase 41 trial
Initiating daily oral PrEP during pregnancyPhase 4
Behavioral: Motivational Enhancement System for PrEP Uptake and AdherenceN/A
PrEP Optimization InterventionsN/A
ePrEPN/A1 trial
Active Trials
NCT03729570Completed217Est. May 2022
NCT04664998Completed212Est. Dec 2023
Relief Therapeutics
Relief TherapeuticsSwitzerland - Geneva
1 program
1
Initiating daily oral PrEP during pregnancyPhase 41 trial
Active Trials
NCT06158126Recruiting621Est. Dec 2027
Allergy Therapeutics
Allergy TherapeuticsUK - West Sussex
4 programs
Blued+ Service PlatformN/A1 trial
Financial IncentiveN/A1 trial
PrEP Optimization InterventionsN/A1 trial
Provision of sexual health preventative services in the salon settingN/A1 trial
Active Trials
NCT06647173Completed423Est. Feb 2024
NCT03078153Completed57Est. Dec 2020
NCT04712994Completed1,958Est. Jan 2022
+1 more trials
Innovation Pharmaceuticals
3 programs
Behavioral: Motivational Enhancement System for PrEP Uptake and AdherenceN/A1 trial
Mobile Healthy ChoicesN/A1 trial
Motivational Enhancement System for PrEP Uptake and AdherenceN/A1 trial
Active Trials
NCT05262426Active Not Recruiting145Est. Jul 2026
NCT06576648Recruiting154Est. Aug 2027
NCT05243030Completed119Est. Jul 2025
Gilead Sciences
Gilead SciencesFOSTER CITY, CA
2 programs
Financial IncentiveN/A
Financial IncentiveN/A
Kite Pharma
Kite PharmaCA - El Segundo
1 program
Financial IncentiveN/A
MediaPharma
MediaPharmaItaly - Chieti
1 program
Social Media CampaignN/A1 trial
Active Trials
NCT05417620Completed601Est. Nov 2023

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
Relief TherapeuticsInitiating daily oral PrEP during pregnancy
Human BioSciencesDaily oral PrEP
Innovation PharmaceuticalsMobile Healthy Choices
MediaPharmaSocial Media Campaign
Allergy TherapeuticsBlued+ Service Platform
Innovation PharmaceuticalsMotivational Enhancement System for PrEP Uptake and Adherence
Innovation PharmaceuticalsBehavioral: Motivational Enhancement System for PrEP Uptake and Adherence
Allergy TherapeuticsPrEP Optimization Interventions
Allergy TherapeuticsProvision of sexual health preventative services in the salon setting
Human BioSciencesePrEP
Allergy TherapeuticsFinancial Incentive

Clinical Trials (11)

Total enrollment: 4,943 patients across 11 trials

NCT06158126Relief TherapeuticsInitiating daily oral PrEP during pregnancy

UNCPM 22314 - Pregnancy, Infant and Maternal Health Outcomes Study

Start: Apr 2024Est. completion: Dec 2027621 patients
Phase 4Recruiting
NCT04664998Human BioSciencesDaily oral PrEP

Alignment of PrEP Use With HIV Risk in Young Women and Men

Start: May 2018Est. completion: Dec 2023212 patients
Phase 4Completed
NCT06576648Innovation PharmaceuticalsMobile Healthy Choices

Thailand HIV and Stigma Reduction Study

Start: Feb 2025Est. completion: Aug 2027154 patients
N/ARecruiting
NCT05417620MediaPharmaSocial Media Campaign

Le Kip Kip: A Campaign to Change Social Norms and Build Sustainable Demand for PrEP Among Women in South Africa

Start: Oct 2022Est. completion: Nov 2023601 patients
N/ACompleted
NCT06647173Allergy TherapeuticsBlued+ Service Platform

The Blued+ Combination HIV Prevention Pilot Study in China

Start: Jul 2022Est. completion: Feb 2024423 patients
N/ACompleted
NCT05243030Innovation PharmaceuticalsMotivational Enhancement System for PrEP Uptake and Adherence

Developing mHealth to Promote PrEP Use Among Thai Young Men Who Have Sex With Men

Start: Feb 2022Est. completion: Jul 2025119 patients
N/ACompleted
NCT05262426Innovation PharmaceuticalsBehavioral: Motivational Enhancement System for PrEP Uptake and Adherence

Developing mHealth to Promote PrEP Use Among Thai Young Vulnerable Adolescents and Emerging Adults

Start: Dec 2021Est. completion: Jul 2026145 patients
N/AActive Not Recruiting
NCT04712994Allergy TherapeuticsPrEP Optimization Interventions

PrEPARE: PrEP in Pregnancy, Accelerating Reach and Efficiency

Start: May 2021Est. completion: Jan 20221,958 patients
N/ACompleted
NCT04222504Allergy TherapeuticsProvision of sexual health preventative services in the salon setting

Community-based Venues for Delivery of Healthcare Services: Proof of Concept Pilot

Start: Feb 2021Est. completion: Mar 2026436 patients
N/ACompleted
NCT03729570Human BioSciencesePrEP

Electronic Pre-exposure Prophylaxis (PrEP) Initiation and Maintenance Home Care System

Start: May 2019Est. completion: May 2022217 patients
N/ACompleted
NCT03078153Allergy TherapeuticsFinancial Incentive

Effect of Social Media Support and Financial Incentives on PrEP Adherence

Start: Apr 2017Est. completion: Dec 202057 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 actively recruiting trials targeting 4,943 patients
8 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.