Pain, Postoperative
Pipeline by Development Stage
Drug Modality Breakdown
On Market (3)
Approved therapies currently available
Competitive Landscape
35 companies ranked by most advanced pipeline stage
+5 more companies
Trial Timeline
Clinical trial activity over time
Showing 15 of 50 trials with date data
Clinical Trials (50)
Total enrollment: 8,933 patients across 50 trials
Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
Post-Op Lidocaine Patch
Evaluation of Abdominal Wall Block With Liposomal Bupivacaine for Post-Operative Analgesia in Donor Nephrectomy
Parecoxib for Pain Management After Total Knee Arthroplasty and Total Hip Arthroplasty
Safety and Efficacy of Cocktail Periarticular Injection in Simultaneous Total Knee Arthroplasty
Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin
Efficacy of Liposomal Bupivacaine Versus 0.25% Bupivacaine for Laparoscopic Urologic Surgery
Use of Local Infiltration Analgesia Following Total Hip Arthroplasty
Local Infiltration Analgesia in Bilateral Knee Arthroplasty - Efficacy of Subcutaneous Wound Infiltration With Local Anesthetic
Postoperative Pain and Functional Patient Outcomes After Functional Endoscopic Sinus Surgery
A Multicentre, Double-Blind, Double-Dummy, Randomised Study of the Analgesic Efficacy and Safety of Valdecoxib Compared to Diclofenac Sodium in Patients Undergoing Knee Arthroscopy for Anterior Cruciate Ligament (ACL) Reconstruction
Ketorolac Applied by Continuous IV Infusion for Treatment of Moderately Severe Postoperative Pain Following Bunionectomy
Efficacy and Safety of VVZ-149 Injections in Patients Undergoing Laparoscopic Colectomy
Phase 3 Efficacy and Safety Study of VVZ-149 Injections for Postoperative Pain Following Bunionectomy
Evaluate the Efficacy and Safety of VVZ-149 Injections for the Treatment of Post-Operative Pain Following Abdominoplasty
Evaluation of Preoperative N1539 in Total Knee Arthroplasty
Evaluation of Preoperative N1539 in Colorectal Surgery
Ropivacaine 0.2% Pre-Filled Dispenser for the Treatment of Postsurgical Pain in Patients Undergoing Cesarean Delivery
Efficacy and Safety of Ibuprofen and Caffeine in Dental Pain
Safety and Efficacy of Repeated Doses of PMI-150 (Intranasal Ketamine) in Acute Post-operative Pain Following Orthopedic Surgery
Surgical Pain After Inguinal Hernia Repair (SPAIHR)
Analgesic Efficacy, Safety and Tolerability of Two Paracetamol-Containing Solutions in Post-Surgical Hip Replacement Pain
Study Of The Efficacy And Safety Of Pregabalin Compared To Placebo For Treatment Of Post-Surgical Pain From Hysterectomy
Analgesic Efficacy, Safety and Tolerability of Two Paracetamol-containing Solutions in Post-Surgical Dental Pain
Compare Celecoxib and Ibuprofen Sr In The Management Of Acute Pain Post Orthopedic Or Gynecological Surgery
Anesthetic Premedication With a Cannabis Extract (Cannapremed)
A Study to Evaluate the Use of Topical Ocular BL1332 for the Management of Postoperative Ocular Pain Following Photorefractive Keratectomy
Phase II Clinical Trial to Evaluate the Efficacy and Safety of LPM3480392 Injection for Moderate to Severe Pain After Abdominal Surgery
Evaluate the Efficacy and Safety of VVZ-149 Injections for the Treatment of Postoperative Pain Following Bunionectomy
Effectiveness of an Opioid Sparing Pain Regimen in Cardiac Surgery
Intrathecal Paracetamol Before Spinal Anaesthesia With Chloroprocaine HCl 1% for Short Knee Procedures
Study to Determine if Pre- and Post- Operative TAP Catheters With Ropivacaine Versus Placebo Affects Anesthetic, Narcotic Dosing, and Pain Scores
Combination Dexamethasone and Bupivacaine Pain Control in Reduction Mammaplasty
An Open-Label Functionality, Safety and Efficacy Study in Patients Undergoing Elective Unilateral Knee Replacement
A Study to Evaluate the Safety and Efficacy of an Investigational Drug in the Treatment of Postoperative Dental Pain (MK-2295-005)
A Study to Evaluate the Efficacy of MK0719 in the Prevention of Postoperative Dental Pain (0719-002)
MK0686 in Postsurgery Dental Pain (0686-002)
Quadratus Lumborum Block for Total Hip Arthroplasty
Study to Evaluate the Safety and Tolerability of FX301 in Patients Undergoing Bunionectomy
Comparison of ESP Block and M-TAPA Block Efficiency in Postoperative Analgesia Management in Nephrectomy Cases
Cryoablation Effects on Acute and Chronic Pain After Thoracotomy and Thoracoscopy
Feasibility of Bridge for Post-Operative Pain Management in Hip Arthroplasty
Healing Touch After Cesarean
Use of Analgesics and Pain Scores After Pediatric Adenotonsillectomy
Sitz Bath vs no Sitz Bath in Acute Anal Fissure Treatment
pMDT in Thoracic Surgery--The Process Implementation Stage
pMDT in Thoracic Surgery--------For the Baseline Investigation and Technical Preparation Stage
Intraperitoneal Lavage for Reducing Pain in Laparoscopy
Spinal Anesthesia and Peri-operative Opioid Consumption in Open Abdominal Prostatectomy
Monitor-Guided Analgesia During General Anesthesia - Part II
Phase Legend
Key Insights
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