Skip to main content

Mycosis Fungoides

4
Pipeline Programs
11
Companies
12
Clinical Trials
4 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
2100%
+ 10 programs with unclassified modality

Competitive Landscape

11 companies ranked by most advanced pipeline stage

Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
1 program
1
A-dmDT390-bisFvPhase 21 trial
Active Trials
NCT02943642Unknown162Est. May 2020
Hope Medicine
Hope MedicineChina - Pudong
1 program
1
A-dmDT390-bisFvPhase 2
Sorrento Therapeutics
Sorrento TherapeuticsCA - San Diego
1 program
1
Pembrolizumab administered using the Sofusa® DoseConnect™Phase 11 trial
Active Trials
NCT04118868Unknown10Est. Mar 2024
Sandoz
SandozAustria - Kundl
1 program
1
TulmimetostatPhase 1Small Molecule
Recordati
RecordatiFrance - Saint-Victor
2 programs
ChlormethineN/A
The Mechanism of Action of Chlormethine (CL) Gel in the Treatment of MF-CTCL Adult PatientsN/A1 trial
Active Trials
NCT06421571Recruiting40Est. Dec 2025
Human BioSciences
Human BioSciencesWV - Martinsburg
1 program
ChlormethineN/A1 trial
Active Trials
NCT05303480Completed32Est. Dec 2022
Helsinn
HelsinnIreland - Dublin
1 program
ValchlorN/A1 trial
Active Trials
NCT02296164Completed300Est. Oct 2018
Bausch Health
Bausch HealthQUEBEC, Quebec, Canada
1 program
imiquimodN/A2 trials
Active Trials
NCT02301494Withdrawn0Est. Apr 2023
NCT03914417Completed21Est. Apr 2015
Kyowa Hakko Kirin
Kyowa Hakko KirinCA - La Jolla
1 program
Mogamulizumab-KpkcPHASE_11 trial
Active Trials
NCT06235281Suspended20Est. Sep 2029
Novartis
NovartisBASEL, Switzerland
1 program
TulmimetostatPHASE_1Small Molecule4 trials
Active Trials
NCT07190300Recruiting155Est. Aug 2032
NCT07206056Recruiting188Est. Dec 2030
NCT05944562Active Not Recruiting24Est. Jan 2029
+1 more trials
City Therapeutics
City TherapeuticsMA - Cambridge
1 program
A-dmDT390-bisFvPHASE_2

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Colorado TherapeuticsA-dmDT390-bisFv
Bausch Healthimiquimod
NovartisTulmimetostat
NovartisTulmimetostat
NovartisTulmimetostat
Kyowa Hakko KirinMogamulizumab-Kpkc
NovartisTulmimetostat
Sorrento TherapeuticsPembrolizumab administered using the Sofusa® DoseConnect™
RecordatiThe Mechanism of Action of Chlormethine (CL) Gel in the Treatment of MF-CTCL Adult Patients
Human BioSciencesChlormethine
Bausch Healthimiquimod
HelsinnValchlor

Clinical Trials (12)

Total enrollment: 1,227 patients across 12 trials

Safety and Effectiveness of A-dmDT390-bisFv(UCHT1) Fusion Protein in Subjects With Mycosis Fungoides

Start: Jan 2017Est. completion: May 2020162 patients
Phase 2Unknown

Genomic Markers Before and After Treatment of Actinic Keratosis With Imiquimod 3.75% Cream

Start: Jan 2013Est. completion: Apr 201521 patients
Phase 2Completed
NCT07190300NovartisTulmimetostat

TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Start: Jan 2026Est. completion: Aug 2032155 patients
Phase 1/2Recruiting
NCT07206056NovartisTulmimetostat

An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)

Start: Oct 2025Est. completion: Dec 2030188 patients
Phase 1/2Recruiting
NCT04104776NovartisTulmimetostat

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

Start: Sep 2019Est. completion: Feb 2030275 patients
Phase 1/2Recruiting

Phototherapy and Mogamulizumab in Early Stage MF (PLIGHT)

Start: Jan 2024Est. completion: Sep 202920 patients
Phase 1Suspended
NCT05944562NovartisTulmimetostat

Tulmimetostat (DZR123) in Patients With Mycosis Fungoides and Sézary Syndrome

Start: Jan 2024Est. completion: Jan 202924 patients
Phase 1Active Not Recruiting
NCT04118868Sorrento TherapeuticsPembrolizumab administered using the Sofusa® DoseConnect™

Pembrolizumab Administered Via the Sofusa® DoseConnect™ in Patients With Relapsed/Refractory Cutaneous T-cell Lymphoma.

Start: Aug 2022Est. completion: Mar 202410 patients
Phase 1Unknown
NCT06421571RecordatiThe Mechanism of Action of Chlormethine (CL) Gel in the Treatment of MF-CTCL Adult Patients

The Mechanism of Action of Chlormethine (CL) Gel in the Treatment of MF-CTCL Adult Patients

Start: Feb 2023Est. completion: Dec 202540 patients
N/ARecruiting

Deep Phenotyping of Cutaneous T Cell Lymphoma, Type Mycosis Fungoides

Start: Dec 2021Est. completion: Dec 202232 patients
N/ACompleted

Effectiveness of Imiquimod Topical Cream in Early Stage Cutaneous T-cell Lymphoma

Start: Apr 2020Est. completion: Apr 20230
N/AWithdrawn

Clinical Study Assessing Outcomes, Adverse Events, Treatment Patterns, and Quality of Life in Patients Diagnosed With Mycosis Fungoides Cutaneous T-cell Lymphoma

Start: Nov 2014Est. completion: Oct 2018300 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

4 actively recruiting trials targeting 1,227 patients
11 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.