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Mechanical Ventilation

4
Pipeline Programs
11
Companies
8
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
2
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

10 companies ranked by most advanced pipeline stage

Pfizer
PfizerNEW YORK, NY
1 program
1
DexmedetomidinePhase 41 trial
Active Trials
NCT01059929Terminated41Est. Sep 2015
Human BioSciences
Human BioSciencesWV - Martinsburg
1 program
1
AcetaminophenPhase 31 trial
Active Trials
NCT06994442Recruiting644Est. Aug 2029
ViiV Healthcare
ViiV HealthcareNC - Durham
1 program
1
RemifentanylPhase 3
Sandoz
SandozAustria - Kundl
1 program
1
BYM338Phase 21 trial
Active Trials
NCT01868685Withdrawn0Est. Jan 2015
City Therapeutics
City TherapeuticsMA - Cambridge
1 program
Mechanical VentilationN/A1 trial
Active Trials
NCT06625099CompletedEst. Oct 2025
Innovation Pharmaceuticals
1 program
RespirAq HumidificationN/A1 trial
Active Trials
NCT04765878Unknown20Est. Apr 2021
UNION therapeutics
UNION therapeuticsDenmark - Hellerup
1 program
Sodium Glycerophosphate 216 MG/MLN/A1 trial
Active Trials
NCT06754670Recruiting70Est. Aug 2025
Novartis
NovartisBASEL, Switzerland
1 program
BYM338PHASE_2
Francis Medical
Francis MedicalMN - Maple Grove
1 program
CAMPHASE_21 trial
Active Trials
NCT00663637Unknown30
GSK
GSKLONDON, United Kingdom
1 program
RemifentanylPHASE_31 trial
Active Trials
NCT00419601Completed24Est. Apr 2010

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
PfizerDexmedetomidine
Human BioSciencesAcetaminophen
GSKRemifentanyl
SandozBYM338
Francis MedicalCAM
UNION therapeuticsSodium Glycerophosphate 216 MG/ML
City TherapeuticsMechanical Ventilation
Innovation PharmaceuticalsRespirAq Humidification

Clinical Trials (8)

Total enrollment: 829 patients across 8 trials

NCT01059929PfizerDexmedetomidine

Dexmedetomidine Versus Propofol in the Medical Intensive Care Unit (MICU)

Start: Sep 2009Est. completion: Sep 201541 patients
Phase 4Terminated
NCT06994442Human BioSciencesAcetaminophen

Optimizing Pain Treatment in Children On Mechanical Ventilation

Start: Dec 2025Est. completion: Aug 2029644 patients
Phase 3Recruiting
NCT00419601GSKRemifentanyl

Rapip Study: Clinical Trial on Remifentanyl for Analgesia and Sedation of Ventilated Neonates and Infants

Start: Nov 2006Est. completion: Apr 201024 patients
Phase 3Completed
NCT01868685SandozBYM338

Study of Muscle Effects of BYM338 in Mechanically Ventilated Patients

Start: Apr 2014Est. completion: Jan 20150
Phase 2Withdrawn
NCT00663637Francis MedicalCAM

Removal of Endotracheal Tube Secretions Comprehensively Until Extubation

Start: Apr 200830 patients
Phase 2Unknown
NCT06754670UNION therapeuticsSodium Glycerophosphate 216 MG/ML

Effect of Hypophosphatemia on Neuro-excursion Efficiency During Mechanical Ventilator Weaning

Start: Oct 2024Est. completion: Aug 202570 patients
N/ARecruiting
NCT06625099City TherapeuticsMechanical Ventilation

Investigation of the Optimum PEEP Mechanical Power Relationship

Start: Sep 2024Est. completion: Oct 2025
N/ACompleted
NCT04765878Innovation PharmaceuticalsRespirAq Humidification

RespirAq Humidifier Usability During Invasive Ventilation

Start: Mar 2021Est. completion: Apr 202120 patients
N/AUnknown

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 late-stage (Phase 3) programs, potential near-term approvals
2 actively recruiting trials targeting 829 patients
11 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.