Malignant Pleural Effusion
1
Pipeline Programs
3
Companies
3
Clinical Trials
0
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket
Drug Modality Breakdown
Small Molecule
1100%
+ 2 programs with unclassified modality
Competitive Landscape
3 companies ranked by most advanced pipeline stage
Candel TherapeuticsNEEDHAM, MA
1 program1
AdV-tk + valacyclovirPhase 1Small Molecule1 trial
Active Trials
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
Candel TherapeuticsAdV-tk + valacyclovir
Rocket PharmaceuticalsPleural procedures
Merit MedicalAspira Catheter
Clinical Trials (3)
Total enrollment: 50 patients across 3 trials
Intrapleural AdV-tk Therapy in Patients With Malignant Pleural Effusion
Start: Oct 2013Est. completion: Feb 2018
Phase 1Completed
Interventions for Malignant Pleural Effusions Impact on Fatigue
Start: Sep 2020Est. completion: Oct 202150 patients
N/AUnknown
Management of Malignant Pleural Effusions Using an Indwelling Tunneled Pleural Catheter and Non-Vacuum Collection System
Start: Jul 2018Est. completion: Feb 2024
N/ACompleted
Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
3 companies competing in this space