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Lymphoid Malignancies

8
Pipeline Programs
6
Companies
6
Clinical Trials
1 recruiting
2
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
3
2
0
0
0
3
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
3100%
+ 7 programs with unclassified modality

On Market (2)

Approved therapies currently available

Gilead Sciences
IDELALISIBApproved
idelalisib
Gilead Sciences
oral2026
Gilead Sciences
ZYDELIGApproved
idelalisib
Gilead Sciences
Kinase Inhibitor [EPC]oral2014

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Gilead Sciences
Gilead SciencesFOSTER CITY, CA
4 programs
1
GS-9820PHASE_1
GS-9820PHASE_1
IdelalisibPHASE_4Small Molecule
IdelalisibPHASE_4Small Molecule
Kite Pharma
Kite PharmaCA - El Segundo
2 programs
1
1
IdelalisibPhase 4Small Molecule1 trial
GS-9820Phase 11 trial
Active Trials
NCT01705847Completed39Est. May 2016
NCT02739360Terminated3Est. Dec 2017
Medpace
MedpaceCINCINNATI, OH
1 program
1
AVM0703Phase 1/2
AVM Biotechnology
AVM BiotechnologyWA - Seattle
1 program
1
AVM0703Phase 1/23 trials
Active Trials
NCT05974410Available
NCT04366115Not Yet Recruiting16Est. Mar 2032
NCT04329728Recruiting144Est. Dec 2028
Genome & Company
Genome & CompanyKorea - Suwon
1 program
1
HGS1029Phase 11 trial
Active Trials
NCT01013818Terminated11Est. Oct 2011
Human BioSciences
Human BioSciencesWV - Martinsburg
1 program
1
HGS1029Phase 1

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Kite PharmaIdelalisib
AVM BiotechnologyAVM0703
AVM BiotechnologyAVM0703
Kite PharmaGS-9820
Genome & CompanyHGS1029

Clinical Trials (6)

Total enrollment: 213 patients across 6 trials

Roll Over Study to Provide Idelalisib to Participants Previously Treated With the Investigational PI3Kδ Inhibitor, GS-9820

Start: May 2016Est. completion: Dec 20173 patients
Phase 4Terminated

The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies

Start: Nov 2020Est. completion: Dec 2028144 patients
Phase 1/2Recruiting

Evaluating AVM0703 for Treatment of COVID-19 or Influenza-mediated ARDS

Start: Dec 2026Est. completion: Mar 203216 patients
Phase 1Not Yet Recruiting

A Phase 1b Study Evaluating GS-9820 in Subjects With Lymphoid Malignancies

Start: Nov 2012Est. completion: May 201639 patients
Phase 1Completed

A Study of HGS1029 in Subjects With Relapsed or Refractory Lymphoid Malignancies

Start: Oct 2009Est. completion: Oct 201111 patients
Phase 1Terminated

Expanded Access to Immunomodulatory AVM0703 for Solid Tumor and Blood Cancer Patients

N/AAvailable

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 213 patients
6 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.

Lymphoid Malignancies | Pipeline & Competitive Landscape | Formulate