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Lymphoid Malignancies

7
Pipeline Programs
5
Companies
6
Clinical Trials
1 recruiting
2
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
2
0
0
0
3
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
3100%
+ 6 programs with unclassified modality

On Market (2)

Approved therapies currently available

Gilead Sciences
IDELALISIBApproved
idelalisib
Gilead Sciences
oral2026
Gilead Sciences
ZYDELIGApproved
idelalisib
Gilead Sciences
Kinase Inhibitor [EPC]oral2014

Competitive Landscape

5 companies ranked by most advanced pipeline stage

Gilead Sciences
Gilead SciencesFOSTER CITY, CA
4 programs
1
GS-9820PHASE_11 trial
GS-9820PHASE_1
IdelalisibPHASE_4Small Molecule
IdelalisibPHASE_4Small Molecule1 trial
Active Trials
NCT01705847Completed39Est. May 2016
NCT02739360Terminated3Est. Dec 2017
Kite Pharma
Kite PharmaCA - El Segundo
2 programs
1
1
IdelalisibPhase 4Small Molecule
GS-9820Phase 1
Medpace
MedpaceCINCINNATI, OH
1 program
1
AVM0703Phase 1/2
AVM Biotechnology
AVM BiotechnologyWA - Seattle
1 program
1
AVM0703Phase 1/23 trials
Active Trials
NCT05974410Available
NCT04366115Not Yet Recruiting16Est. Mar 2032
NCT04329728Recruiting144Est. Dec 2026
Genome & Company
Genome & CompanyKorea - Suwon
1 program
1
HGS1029Phase 11 trial
Active Trials
NCT01013818Terminated11Est. Oct 2011

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Gilead SciencesIdelalisib
AVM BiotechnologyAVM0703
AVM BiotechnologyAVM0703
Gilead SciencesGS-9820
Genome & CompanyHGS1029

Clinical Trials (6)

Total enrollment: 213 patients across 6 trials

Roll Over Study to Provide Idelalisib to Participants Previously Treated With the Investigational PI3Kδ Inhibitor, GS-9820

Start: May 2016Est. completion: Dec 20173 patients
Phase 4Terminated

The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies

Start: Nov 2020Est. completion: Dec 2026144 patients
Phase 1/2Recruiting

Evaluating AVM0703 for Treatment of COVID-19 or Influenza-mediated ARDS

Start: Dec 2026Est. completion: Mar 203216 patients
Phase 1Not Yet Recruiting

A Phase 1b Study Evaluating GS-9820 in Subjects With Lymphoid Malignancies

Start: Nov 2012Est. completion: May 201639 patients
Phase 1Completed

A Study of HGS1029 in Subjects With Relapsed or Refractory Lymphoid Malignancies

Start: Oct 2009Est. completion: Oct 201111 patients
Phase 1Terminated

Expanded Access to Immunomodulatory AVM0703 for Solid Tumor and Blood Cancer Patients

N/AAvailable

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 213 patients
5 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.