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Infertility, Female

9
Pipeline Programs
18
Companies
27
Clinical Trials
4 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
2
1
0
1
3
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

17 companies ranked by most advanced pipeline stage

Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
1 program
1
CFAPhase 4
MSD
MSDIreland - Ballydine
1 program
1
CFAPhase 41 trial
Active Trials
NCT03755973Completed24Est. May 2023
Eppendorf
EppendorfGermany - Hamburg
1 program
1
Dydrogesterone Oral TabletPhase 4
Human BioSciences
Human BioSciencesWV - Martinsburg
4 programs
1
2
1
Caloric RestrictionPhase 31 trial
G-CSFPhase 1/21 trial
G-CSFPhase 1/21 trial
MicrodialysisPhase 1
Active Trials
NCT01202643Terminated12Est. Feb 2013
NCT01202656Completed129Est. Jun 2013
NCT02432209Completed379Est. May 2020
Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
2 programs
1
1
Estradiol PatchesPhase 21 trial
MicrodialysisPhase 11 trial
Active Trials
NCT01817400Completed10Est. Dec 2014
NCT06686537Recruiting20Est. Dec 2026
Ferring Pharmaceuticals
Ferring PharmaceuticalsArgentina - Buenos Aires
7 programs
MENOPUR CohortN/A1 trial
Other: Non interventionN/A1 trial
A MENOPUR solution for injection in pre-filled pen, 600 IU/0.96 mLPHASE_11 trial
Degarelix mid-luteal, 2.5 mgPHASE_21 trial
FE 999049PHASE_31 trial
+2 more programs
Active Trials
NCT04814940Withdrawn0Est. Sep 2023
NCT04654039Completed728Est. Oct 2023
NCT04902131Completed95Est. Aug 2022
+4 more trials
Genomic Prediction
Genomic PredictionNJ - Hackettstown
3 programs
Preimplantation genetic testing for aneuploidyN/A1 trial
Preimplantation genetic testing for aneuploidyN/A1 trial
Spent media collectionN/A1 trial
Active Trials
NCT06141135Recruiting240Est. Nov 2026
NCT04167748Recruiting240Est. Dec 2026
NCT04628507Not Yet Recruiting200Est. Dec 2027
Genesis Therapeutics
Genesis TherapeuticsCA - Burlingame
2 programs
Autologous PRP intra ovarian infusionPHASE_2_31 trial
Autologous Platelet Rich PlasmaPHASE_2_31 trial
Active Trials
NCT03916978RecruitingEst. Jul 2026
NCT03951194UnknownEst. Jul 2025
Merck & Co.
Merck & Co.RAHWAY, NJ
2 programs
Pre-treatment with rLHPHASE_31 trial
CFAPHASE_4
Active Trials
NCT03741699Completed88Est. May 2024
Innovation Pharmaceuticals
1 program
EmbryORP®N/A1 trial
Active Trials
NCT05919186Completed293Est. May 2022
Clarity Pharmaceuticals
Clarity PharmaceuticalsAustralia - Eveleigh
1 program
Follicle ClarityN/A1 trial
Active Trials
NCT04545918Unknown80Est. May 2021
ConvaTec
ConvaTecNJ - Bridgewater
1 program
IVF with the Neria™ Guard Subcutaneous CatheterN/A1 trial
Active Trials
NCT05505474Unknown100Est. Dec 2024
Lo.Li. Pharma
Lo.Li. PharmaItaly - Rome
1 program
Inofolic PlusN/A1 trial
Active Trials
NCT01290432Completed15Est. Feb 2012
Overture Life
Overture LifeFL - Coral Gables
1 program
Investigational device named ICSIAN/A1 trial
Active Trials
NCT05633316Unknown10Est. Nov 2024
Genomics
GenomicsUK - Oxford
1 program
Timelapse incubation and PGTN/A1 trial
Active Trials
NCT06419127Enrolling By Invitation2,000Est. Jun 2033
Gedeon Richter
Gedeon RichterHungary - Budapest
1 program
ULIPRISTAL ACETATEN/A1 trial
Active Trials
NCT03349190Completed127Est. Jan 2019
Qilu Pharmaceutical
Qilu PharmaceuticalChina - Jinan
1 program
QL1012DPHASE_11 trial
Active Trials
NCT06864793Active Not Recruiting48Est. Apr 2026

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
MSDCFA
Ferring PharmaceuticalsFE 999049
Ferring PharmaceuticalsFE 999049 + GnRH agonist
Merck & Co.Pre-treatment with rLH
Ferring PharmaceuticalsFollitropin delta
Human BioSciencesCaloric Restriction
Genesis TherapeuticsAutologous Platelet Rich Plasma
Genesis TherapeuticsAutologous PRP intra ovarian infusion
Colorado TherapeuticsEstradiol Patches
Ferring PharmaceuticalsDegarelix mid-luteal, 2.5 mg
Human BioSciencesG-CSF
Human BioSciencesG-CSF
Qilu PharmaceuticalQL1012D
Ferring PharmaceuticalsA MENOPUR solution for injection in pre-filled pen, 600 IU/0.96 mL
Colorado TherapeuticsMicrodialysis

Showing 15 of 27 trials with date data

Clinical Trials (27)

Total enrollment: 6,249 patients across 27 trials

Effect of Different Ovarian Stimulation Protocols on Endometrial Receptivity

Start: Jan 2020Est. completion: May 202324 patients
Phase 4Completed

A Randomised Trial Comparing the Ovarian Response of a Starting Dose of Either 10 μg or 15 μg Follitropin Delta (FE 999049) to a Starting Dose of Either 150 IU or 225 IU Follitropin Alfa (GONAL-F) in Conventional Regimens in China

Start: Mar 2024Est. completion: May 2025301 patients
Phase 3Completed
NCT03809429Ferring PharmaceuticalsFE 999049 + GnRH agonist

Follitropin Delta in Long GnRH Agonist and GnRH Antagonist Protocols (BEYOND)

Start: Apr 2019Est. completion: Feb 2022437 patients
Phase 3Completed
NCT03741699Merck & Co.Pre-treatment with rLH

Recombinant LH Prior to Ovarian Stimulation in Poor Ovarian Responders (PRE-LH)

Start: Feb 2019Est. completion: May 202488 patients
Phase 3Completed

Recombinant FSH Investigation in the Treatment of Infertility With Assisted Reproductive Technology (ART) (RITA-2)

Start: Oct 2018Est. completion: Dec 2020588 patients
Phase 3Completed
NCT02432209Human BioSciencesCaloric Restriction

Improving Reproductive Fitness Through Pretreatment With Lifestyle Modification in Obese Women With Unexplained Infertility

Start: Aug 2015Est. completion: May 2020379 patients
Phase 3Completed
NCT03951194Genesis TherapeuticsAutologous Platelet Rich Plasma

Autologous Platelet Rich Plasma (PRP) Intra Ovarian Infusion in Perimenopausal Women

Start: Jun 2019Est. completion: Jul 2025
Phase 2/3Unknown
NCT03916978Genesis TherapeuticsAutologous PRP intra ovarian infusion

Autologous PRP Intra Ovarian Infusion to Restore Ovarian Function in Menopausal Women

Start: May 2019Est. completion: Jul 2026
Phase 2/3Recruiting

Convergent Mechanisms Underlying Reprometabolic Syndrome in Women

Start: Feb 2025Est. completion: Dec 202620 patients
Phase 2Recruiting
NCT00434122Ferring PharmaceuticalsDegarelix mid-luteal, 2.5 mg

Exploratory Study Assessing Synchronisation of Egg Sacs With Degarelix

Start: Mar 2007Est. completion: Dec 200785 patients
Phase 2Completed

Effect of Colony Stimulating Factor on Implantation and Pregnancy Rates Following IVF (in Vitro Fertilization)

Start: Sep 2010Est. completion: Jun 2013129 patients
Phase 1/2Completed

Effect of Colony Stimulating Factor on Poor Endometrial Development During IVF

Start: Sep 2010Est. completion: Feb 201312 patients
Phase 1/2Terminated

Study on the Pharmacokinetics and Safety of QL1012D and Gonal-F® in Healthy Female Volunteers

Start: Apr 2025Est. completion: Apr 202648 patients
Phase 1Active Not Recruiting
NCT04902131Ferring PharmaceuticalsA MENOPUR solution for injection in pre-filled pen, 600 IU/0.96 mL

A Study Comparing MENOPUR in a Pen Formulation With a Powder and Solvent Formulation in Healthy Women

Start: Nov 2021Est. completion: Aug 202295 patients
Phase 1Completed

Mediators of Abnormal Reproductive Function in Obesity (MARO)

Start: Mar 2013Est. completion: Dec 201410 patients
Phase 1Completed
NCT04628507Genomic PredictionSpent media collection

Cell Free Preimplantation Genetic Testing

Start: Jun 2026Est. completion: Dec 2027200 patients
N/ANot Yet Recruiting
NCT06419127GenomicsTimelapse incubation and PGT

Embryo Assessment Utilizing Timelapse Imaging in Conjunction With Preimplantation Genetic Testing for Aneuploidy With Next Generation Sequencing

Start: Jan 2025Est. completion: Jun 20332,000 patients
N/AEnrolling By Invitation
NCT06141135Genomic PredictionPreimplantation genetic testing for aneuploidy

GEnetic Testing in Elective Single Embryo Transfer (GETSET): A Randomized Clinical Trial

Start: Nov 2023Est. completion: Nov 2026240 patients
N/ARecruiting
NCT05505474ConvaTecIVF with the Neria™ Guard Subcutaneous Catheter

Use of a Subcutaneous Catheter for Controlled Ovarian Stimulation

Start: Nov 2023Est. completion: Dec 2024100 patients
N/AUnknown
NCT05633316Overture LifeInvestigational device named ICSIA

Automated Intracytoplasmic Sperm Injection (ICSIA)

Start: Dec 2022Est. completion: Nov 202410 patients
N/AUnknown

Retrospective Analysis of Real-world Data From Medical Records on the Use of MENOPUR for Infertility Treatment

Start: Sep 2022Est. completion: Sep 20230
N/AWithdrawn

Effects of Antioxidant Supplementation of Culture Media on IVF Embryos

Start: Oct 2021Est. completion: May 2022293 patients
N/ACompleted
NCT04167748Genomic PredictionPreimplantation genetic testing for aneuploidy

Preimplantation Genetic Testing in Women of Advanced Maternal Age

Start: Mar 2021Est. completion: Dec 2026240 patients
N/ARecruiting

Convolutional Neural Network in Ovarian Follicle Identification

Start: Feb 2021Est. completion: May 202180 patients
N/AUnknown
NCT04654039Ferring PharmaceuticalsOther: Non intervention

Post-Marketing Surveillance (PMS) Protocol of REKOVELLE Pre-Filled Pen (Follitropin Delta)

Start: Oct 2020Est. completion: Oct 2023728 patients
N/ACompleted
NCT03349190Gedeon RichterULIPRISTAL ACETATE

Impact of Esmya on Fertility to Infertile Women With Fibroids Managed With Assisted Reproduction Techniques

Start: Dec 2017Est. completion: Jan 2019127 patients
N/ACompleted

The Potential Effects of Inofolic Plus on Abnormal Ovarian Reserve Parameters in Subfertile Women

Start: Feb 2011Est. completion: Feb 201215 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs, potential near-term approvals
4 actively recruiting trials targeting 6,249 patients
18 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.