Hypothyroidism

Endocrinology
15
Pipeline Programs
7
Companies
6
Clinical Trials
1 recruiting
10
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
1
0
13
Early DiscoveryClinical DevelopmentMarket

On Market (10)

Approved therapies currently available

U
IOHEXOLApproved
iohexol
Unknown Company
Radiographic Contrast Agent [EPC]injection, oral, rectal2025
U
OMNIPAQUE 12Approved
iohexol
Unknown Company
Radiographic Contrast Agent [EPC]oral1985
U
OMNIPAQUE 140Approved
iohexol
Unknown Company
Radiographic Contrast Agent [EPC]injection1985
U
OMNIPAQUE 180Approved
iohexol
Unknown Company
Radiographic Contrast Agent [EPC]injection, oral, rectal1985
U
OMNIPAQUE 210Approved
iohexol
Unknown Company
Radiographic Contrast Agent [EPC]injection1985
U
OMNIPAQUE 240Approved
iohexol
Unknown Company
Radiographic Contrast Agent [EPC]injection, oral, rectal1995
U
OMNIPAQUE 300Approved
iohexol
Unknown Company
Radiographic Contrast Agent [EPC]injection, oral, rectal1995
U
OMNIPAQUE 350Approved
iohexol
Unknown Company
Radiographic Contrast Agent [EPC]injection, oral1985
U
OMNIPAQUE 70Approved
iohexol
Unknown Company
Radiographic Contrast Agent [EPC]urethral1985
U
OMNIPAQUE 9Approved
iohexol
Unknown Company
Radiographic Contrast Agent [EPC]oral1985

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Eli Lilly and Company
Eli Lilly and CompanyINDIANAPOLIS, IN
1 program
1
Growth hormonePhase 41 trial
Active Trials
NCT00206375Terminated16Est. Nov 2011
Guerbet
GuerbetFrance - Villepinte
1 program
1
IohexolPhase 41 trial
Active Trials
NCT03631771Withdrawn0Est. Feb 2025
M&
Merck & Co.RAHWAY, NJ
1 program
1
Quantitative POC TSH KitPhase 41 trial
Active Trials
NCT01921452CompletedEst. Feb 2014
AbbVie
AbbVieNORTH CHICAGO, IL
1 program
1
Armour ThyroidPhase 2/31 trial
Active Trials
NCT06345339Recruiting2,800Est. Jun 2028
Takeda
TakedaTOKYO, Japan
1 program
1
Levothyroxine sodium new formulationPhase 21 trial
Active Trials
NCT01916304Completed101Est. Jun 2014
Abbott
AbbottABBOTT PARK, IL
1 program
Blood test for Thyroid stimulating hormoneN/A1 trial
Active Trials
NCT04784208Unknown232Est. Dec 2022

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
GuerbetIohexol
Merck & Co.Quantitative POC TSH Kit
Eli Lilly and CompanyGrowth hormone
AbbVieArmour Thyroid
TakedaLevothyroxine sodium new formulation
AbbottBlood test for Thyroid stimulating hormone

Clinical Trials (6)

Total enrollment: 3,149 patients across 6 trials

NCT03631771GuerbetIohexol

Pediatric Risk of Hypothyroidism With Iodinated Contrast Media

Start: Mar 2022Est. completion: Feb 20250
Phase 4Withdrawn
NCT01921452Merck & Co.Quantitative POC TSH Kit

Study to Verify Clinical Utility of Point-of-Care (POC) Thyroid Stimulating Hormone (TSH) Test Kits as Compared to Third Generation TSH Test Kit

Start: Oct 2013Est. completion: Feb 2014
Phase 4Completed
NCT00206375Eli Lilly and CompanyGrowth hormone

Growth Hormone and GnRH Agonist in Adolescents With Acquired Hypothyroidism

Start: May 2003Est. completion: Nov 201116 patients
Phase 4Terminated
NCT06345339AbbVieArmour Thyroid

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Start: Apr 2024Est. completion: Jun 20282,800 patients
Phase 2/3Recruiting
NCT01916304TakedaLevothyroxine sodium new formulation

Study of Dose Adjustment From Levothyroxine to a New Levothyroxine Sodium Test Formulation

Start: Jul 2013Est. completion: Jun 2014101 patients
Phase 2Completed
NCT04784208AbbottBlood test for Thyroid stimulating hormone

A Study to Determine the Validity and Sensitivity of 'Questionnaire to Screen for HYpothyroidism' (Q'SHY)

Start: Jan 2021Est. completion: Dec 2022232 patients
N/AUnknown

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 3,149 patients
7 companies competing in this space

Related Indications

Acromegaly(67)Growth Hormone Deficiency(39)Growth Hormone Disorder(37)Hypogonadism(21)Secondary Hyperparathyroidism(13)Hypoparathyroidism(12)Thyroid Eye Disease(11)Adult Growth Hormone Deficiency(10)Cushing's Syndrome(9)Growth Hormone Deficiency in Children(5)