ORGOVYX

Peak

relugolix

NDAORALTABLETPriority Review
Approved
Dec 2020
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
11

Mechanism of Action

Gonadotropin Releasing Hormone Receptor Antagonists

Pharmacologic Class:

Gonadotropin Releasing Hormone Receptor Antagonist

Clinical Trials (5)

NCT06650579Phase 3Recruiting

REVELUTION-2: Relugolix+Abiraterone Acetate (AA) Versus Leuprolide+AA Cardiac Trial

Started Jan 2025
72 enrolled
Recurrent Prostate CarcinomaStage III Prostate Cancer AJCC v8Stage IVA Prostate Cancer AJCC v8
NCT06130995Phase 1Recruiting

Relugolix + Enzalutamide Study in High-Risk Prostate Cancer

Started Dec 2024
46 enrolled
Androgen Deprivation TherapyLocally Advanced Prostate Cancer
NCT06463457Phase 2Active Not Recruiting

Comeback From Long coursE Androgen Deprivation Therapy (ADT) With RElugolix and Darolutamide (CLEARED)

Started Dec 2024
33 enrolled
Prostate CancerAdvanced Prostate CancerHormone Sensitive Prostate Cancer
NCT06631521Phase 1Recruiting

Neoadjuvant Darolutamide and Relugolix Combination Preceding Radical Prostatectomy for Prostate Cancer

Started Oct 2024
30 enrolled
Prostate CAProstate Cancer (Adenocarcinoma)Prostate Cancer Surgery
NCT06330805Phase 2Recruiting

Effects of Relugolix vs Leuprolide on Cardiac Function in Patients With Prostate Cancer

Started Aug 2024
70 enrolled
Prostate AdenocarcinomaStage IIB Prostate Cancer AJCC v8Stage IIC Prostate Cancer AJCC v8

Loss of Exclusivity

LOE Date
Sep 29, 2037
140 months away
Patent Expiry
Sep 29, 2037

Patent Records (5)

Patent #ExpiryTypeUse Code
8058280
Jan 28, 2026Expired
SubstanceProduct
7300935
Jan 28, 2029
Substance
11795178
Sep 27, 2033
SubstanceProduct
12325714
Sep 27, 2033
SubstanceProduct
10350170
Feb 25, 2036
Product