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Headache

3
Pipeline Programs
11
Companies
9
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
2
0
0
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

10 companies ranked by most advanced pipeline stage

Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
2 programs
1
Sphenopalatine ganglion BlockPhase 41 trial
Clinical estrogen therapyN/A1 trial
Active Trials
NCT05607303Active Not Recruiting140Est. Jun 2026
NCT02962427Terminated4Est. Dec 2018
Dexa Medica
Dexa MedicaIndonesia - Tangerang
1 program
1
Predimenol tabletPhase 2
Medica Corp
Medica CorpMA - Bedford
1 program
1
Predimenol tabletPhase 21 trial
Active Trials
NCT06558006Completed60Est. Oct 2024
Labcorp
LabcorpBURLINGTON, NC
1 program
LACIME Anti-hangoverN/A1 trial
Active Trials
NCT04183842Completed40Est. Sep 2019
Verona Pharma
Verona PharmaUK - London
1 program
Manipulative articulatoryN/A1 trial
Active Trials
NCT02953015Unknown16Est. Dec 2017
Biocorp
BiocorpFrance - Issoire
1 program
Myofascial ReleaseN/A1 trial
Active Trials
NCT05990153Unknown100Est. Apr 2026
MSD
MSDIreland - Ballydine
1 program
Online Migraine Treatment OptimizationN/A1 trial
Active Trials
NCT02473692Withdrawn0Est. Dec 2017
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
1 program
Online Migraine Treatment OptimizationN/A
City Therapeutics
City TherapeuticsMA - Cambridge
1 program
Virtual RealityN/A1 trial
Active Trials
NCT06155669CompletedEst. Dec 2024
Heidelberg Pharma
Heidelberg PharmaGermany - Ladenburg
1 program
lumbar puncture with Quincke-design needlesN/A1 trial
Active Trials
NCT00450060Unknown150Est. Dec 2007

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Colorado TherapeuticsSphenopalatine ganglion Block
Medica CorpPredimenol tablet
City TherapeuticsVirtual Reality
BiocorpMyofascial Release
Colorado TherapeuticsClinical estrogen therapy
LabcorpLACIME Anti-hangover
MSDOnline Migraine Treatment Optimization
Verona PharmaManipulative articulatory
Heidelberg Pharmalumbar puncture with Quincke-design needles

Clinical Trials (9)

Total enrollment: 510 patients across 9 trials

NCT02962427Colorado TherapeuticsSphenopalatine ganglion Block

Treatment of Post-dural Puncture Headache in Postpartum Patients: Sphenopalatine Ganglion Block to Epidural Blood Patch.

Start: Nov 2016Est. completion: Dec 20184 patients
Phase 4Terminated
NCT06558006Medica CorpPredimenol tablet

Safety and Efficacy Predimenol for Headache

Start: Jun 2024Est. completion: Oct 202460 patients
Phase 2Completed

The Use of Virtual Reality Applications in Tension-Type Headaches

Start: Dec 2023Est. completion: Dec 2024
N/ACompleted
NCT05990153BiocorpMyofascial Release

Evaluation of the Efficacy of Manual Therapy, Therapeutic Exercise and the Two Modalities Combined in Pain Reduction in Patients With Headache

Start: Apr 2023Est. completion: Apr 2026100 patients
N/AUnknown
NCT05607303Colorado TherapeuticsClinical estrogen therapy

Effect of Hormones on Frequency of Headache and Brain Structure and Function in Puberty

Start: Dec 2021Est. completion: Jun 2026140 patients
N/AActive Not Recruiting
NCT04183842LabcorpLACIME Anti-hangover

Evaluation of a Fixed Combination of Herbal Extracts to Prevent Symptoms Alcohol-induced Hangovers

Start: Jul 2019Est. completion: Sep 201940 patients
N/ACompleted
NCT02473692MSDOnline Migraine Treatment Optimization

Facilitating Migraine Medication Adherence and Optimizing Medication Use

Start: Jun 2017Est. completion: Dec 20170
N/AWithdrawn
NCT02953015Verona PharmaManipulative articulatory

Non-pharmacological Management of Chronic Migraine

Start: Jan 2016Est. completion: Dec 201716 patients
N/AUnknown
NCT00450060Heidelberg Pharmalumbar puncture with Quincke-design needles

Juvenile Postlumbar Puncture Headache After Puncture With Needles With Quincke Tip or With Sprotte Tip

Start: Jan 2007Est. completion: Dec 2007150 patients
N/AUnknown

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

11 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.