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Facial Wrinkles

1
Pipeline Programs
4
Companies
6
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
1
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Fitzpatrick Company
Fitzpatrick CompanyON - Waterloo
1 program
1
Babor Ultimate ECM Repair SerumPhase 2/31 trial
Active Trials
NCT06638905Not Yet Recruiting18Est. May 2025
Sanofi
SanofiPARIS, France
2 programs
Hylaform, Hylaform PlusN/A1 trial
NADGLPHASE_31 trial
Active Trials
NCT00288470CompletedEst. Aug 2003
NCT00417469Completed45Est. Feb 2007
Apyx Medical
Apyx MedicalCLEARWATER, FL
1 program
J-PlasmaN/A2 trials
Active Trials
NCT03286283Completed55Est. Nov 2018
NCT02658851Completed100Est. Jun 2017
Galderma
GaldermaTX - Dallas
1 program
hyaluronic acid dermal fillersN/A1 trial
Active Trials
NCT01151436Completed77Est. Feb 2011

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
SanofiNADGL
Fitzpatrick CompanyBabor Ultimate ECM Repair Serum
Apyx MedicalJ-Plasma
Apyx MedicalJ-Plasma
Galdermahyaluronic acid dermal fillers
SanofiHylaform, Hylaform Plus

Clinical Trials (6)

Total enrollment: 295 patients across 6 trials

A Study to Compare Subject Comfort During and After Injections With the Study Products and the Safety of the Non-FDA Approved Product for the Correction of Nasolabial Folds (NLFs)

Start: Jan 2007Est. completion: Feb 200745 patients
Phase 3Completed
NCT06638905Fitzpatrick CompanyBabor Ultimate ECM Repair Serum

Efficacy and Safety of Skincare Serum and Cream for Anti-aging of Facial Skin

Start: Oct 2024Est. completion: May 202518 patients
Phase 2/3Not Yet Recruiting

The Use of J-Plasma® for Dermal Resurfacing

Start: Jan 2018Est. completion: Nov 201855 patients
N/ACompleted

Cold Plasma for the Reduction of Lymphoceles Following PLND

Start: Jun 2016Est. completion: Jun 2017100 patients
N/ACompleted
NCT01151436Galdermahyaluronic acid dermal fillers

Global Management of Facial Rejuvenation With a New Range of Hyaluronic Acid Dermal Fillers

Start: Mar 2010Est. completion: Feb 201177 patients
N/ACompleted
NCT00288470SanofiHylaform, Hylaform Plus

A Double-blinded Evaluation of Safety and Efficacy of Hylaform and Hylaform Plus Compared to Zyplast.

Start: Jun 2002Est. completion: Aug 2003
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

4 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.