Facial Wrinkles

1
Pipeline Programs
2
Companies
3
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Sanofi
SanofiPARIS, France
2 programs
1
NADGLPhase 31 trial
Hylaform, Hylaform PlusN/A1 trial
Active Trials
NCT00288470CompletedEst. Aug 2003
NCT00417469Completed45Est. Feb 2007
Apyx Medical
Apyx MedicalCLEARWATER, FL
1 program
J-PlasmaN/A1 trial
Active Trials
NCT03286283CompletedEst. Nov 2018

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
SanofiNADGL
Apyx MedicalJ-Plasma
SanofiHylaform, Hylaform Plus

Clinical Trials (3)

Total enrollment: 45 patients across 3 trials

A Study to Compare Subject Comfort During and After Injections With the Study Products and the Safety of the Non-FDA Approved Product for the Correction of Nasolabial Folds (NLFs)

Start: Jan 2007Est. completion: Feb 200745 patients
Phase 3Completed

The Use of J-Plasma® for Dermal Resurfacing

Start: Jan 2018Est. completion: Nov 2018
N/ACompleted
NCT00288470SanofiHylaform, Hylaform Plus

A Double-blinded Evaluation of Safety and Efficacy of Hylaform and Hylaform Plus Compared to Zyplast.

Start: Jun 2002Est. completion: Aug 2003
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
2 companies competing in this space