Eye Diseases

4
Pipeline Programs
6
Companies
5
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
1
0
0
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Glaukos
GlaukosALISO VIEJO, CA
1 program
1
iStentPhase 41 trial
Active Trials
NCT00913029CompletedEst. Sep 2012
Alcon
AlconFORT WORTH, TX
1 program
1
Anecortave Acetate Sterile Suspension, 6 mg/mLPhase 21 trial
Active Trials
NCT00315640Completed70Est. Jul 2009
LENZ Therapeutics
LENZ TherapeuticsSOLANA BEACH, CA
1 program
1
Aceclidine + BrimonidinePhase 11 trial
Active Trials
NCT05936489CompletedEst. Oct 2023
AB
Active BiotechSweden - Lund
1 program
1
LaquinimodPhase 11 trial
Active Trials
NCT05187403CompletedEst. Jan 2023
Regeneron
RegeneronTARRYTOWN, NY
1 program
AfliberceptN/A
T-Therapeutics
T-TherapeuticsUK - Cambridge
1 program
DREAM OCTN/A1 trial
Active Trials
NCT05876689CompletedEst. Oct 2024

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
GlaukosiStent
AlconAnecortave Acetate Sterile Suspension, 6 mg/mL
LENZ TherapeuticsAceclidine + Brimonidine
Active BiotechLaquinimod
T-TherapeuticsDREAM OCT

Clinical Trials (5)

Total enrollment: 70 patients across 5 trials

Evaluation of the iStent Versus Two Ocular Hypotensive Agents in Patients With Primary Open-angle Glaucoma (POAG)

Start: May 2009Est. completion: Sep 2012
Phase 4Completed
NCT00315640AlconAnecortave Acetate Sterile Suspension, 6 mg/mL

Anecortave Acetate for Treatment of Steroid Induced Intraocular Pressure (IOP) Elevation

Start: Dec 2005Est. completion: Jul 200970 patients
Phase 2Completed
NCT05936489LENZ TherapeuticsAceclidine + Brimonidine

Plasma Pharmacokinetics and Safety of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Subjects With Presbyopia

Start: Jul 2023Est. completion: Oct 2023
Phase 1Completed

A Study of Laquinimod Eye-drops in Healthy Participants

Start: Dec 2021Est. completion: Jan 2023
Phase 1Completed

Swept Source OCT Imaging With the DREAM VG-OCT

Start: Oct 2023Est. completion: Oct 2024
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

6 companies competing in this space