Diarrhea
Pipeline by Development Stage
Drug Modality Breakdown
On Market (2)
Approved therapies currently available
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30 companies ranked by most advanced pipeline stage
Trial Timeline
Clinical trial activity over time
Showing 15 of 46 trials with date data
Clinical Trials (50)
Total enrollment: 31,977 patients across 50 trials
Rifaximin 200 mg Plus Oral Rehydration vs Oral Rehydration Alone in Children With Acute Diarrhea
Rifaximin for the Secondary Prevention of Recurrent Pouchitis
Steady-State Pharmacokinetics of Rifaximin 550 mg Tablets in Healthy and Hepatically Impaired Subjects
An Alternate Dosing Schedule for Pentavalent Rotavirus Vaccine (RotaTeq)
The Safety/Efficacy of Rifaximin With/Without Lactulose in Participants With A History of Recurrent Hepatic Encephalopathy
Impact of an Antibiotic (Rifaximin) on Liver Scarring in HIV-Infected Patients With Liver Disease
A Comparison of Three Medications to Treat Diarrhea in Adults.
Study to Determine the Best Way to Measure How Quickly the Drug Can Give Relief From Sudden Diarrhea
Study to Evaluate Smecta® vs Placebo on the Time to Recovery Following an Acute Diarrhoea Episode in Adults
Rifaximin, Loperamide and the Combination to Treat Travelers' Diarrhea
Probiotic Therapy in Preventing Gastrointestinal Complications in Patients Undergoing Chemotherapy and Pelvic Radiation Therapy
Lactoferrin and Lysozyme Supplementation for Long-term Diarrhea Sequelae
Clinical Trial in Children Between 3 Months and 14 Years Old to Evaluate the Efficacy and Safety of Gelatin Tannate in the Treatment of Acute Diarrhea (INDIGO)
Controlled Study to Evaluate the Efficacy and Safety of Racecadotril in Infants, Children and Adolescents With Acute Diarrhea
Antibiotics for Children With Severe Diarrhoea
Sulfasalazine in Preventing Acute Diarrhea in Patients With Cancer Who Are Undergoing Pelvic Radiation Therapy
Efficacy of BIO-K+ CL1285® Prophylaxis in the Prevention of Traveler's Diarrhea in Adults
Randomized, Controlled Trial - Lactoferrin Prevention of Diarrhea in Children
Safety and Tolerability Study of Rifaximin in Participants With a History of Hepatic Encephalopathy
Safety, Efficacy and Cost-effectiveness of Racecadotril in Children With Acute Diarrhea in Mexico
Efficacy and Safety of BIO-K + CL1285 in Prevention of Antibiotic-associated Diarrhea in Hospitalized Adult Patients
A Trial to Compare Xifaxan to Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhea (CDAD)
Prevention of Travelers' Diarrhea in Subjects Traveling Outside the U.S.
TEDDY: Spores of Bacillus Clausii in Acute Diarrhoea in Children
Efficacy of an Oral, Killed Enterotoxigenic Escherichia Coli Vaccine in Prevention of Diarrhea in Egyptian Infants and Young Children
Study of BBIL's ROTAVAC® and ROTAVAC 5CM Vaccines in Zambia
Lanreotide Autogel in the Symptomatic Treatment of Refractory Diarrhea
Treatment of Patients With Human Immunodeficiency Virus (HIV)-Related Chronic Diarrhea With Saccharomyces Boulardii or Placebo: A Double Blind Trial
Clinical Study to Assess the Efficacy of IMM-124E (Travelan®) in a Controlled Human Infection Model
Trial of Rifaximin in Probable Alzheimer's Disease
Rifaximin on Visceral Hypersensitivity
Prevention of Diarrheal Disease Due to Infection With Enterotoxigenic E. Coli (ETEC)
Proof-of-Concept Study in Cancer Patients to Assess Efficacy of Elsiglutide in Preventing Chemotherapy-Induced Diarrhea
Safety and Efficacy Study of a Vaccine Against Enterotoxigenic Escherichia Coli (ETEC) to Prevent Moderate to Severe Diarrhea
Study of a Clostridium Difficile Toxoid Vaccine (ACAM-CDIFF™) in Subjects With Clostridium Difficile Infection
The Role of Bacterial Overgrowth and Delayed Intestinal Transit in Hepatic Encephalopathy
Study to Assess the Efficacy and Safety of Rifaximin Administered BID in the Treatment of Patients With Diarrhea-Associated Irritable Bowel Syndrome
OPT-80 in Clostridium Difficile-Associated Diarrhea (CDAD)
Rifaximin for the Treatment of Irritable Bowel Syndrome
Study of Rifaximin in Minimal Hepatic Encephalopathy
Dose Escalation Study to Evaluate Oral Rotavirus Vaccine 116E Live Attenuated in Healthy Infants 8 to 20 Weeks Old
Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy
ACH04 to Assess the Safety and Tolerability in Healthy Adults Subjects
Open-Label Study to Evaluate the Effect of Rifaximin on Midazolam in Normal Healthy Volunteers
A Multicenter Placebo-Controlled Dose Titration Study to Evaluate the Efficacy and Safety of Sandostatin (SMS 201-995) in the Treatment of Patients With Acquired Immunodeficiency Related Diarrhea
A Multicenter Placebo-Controlled Double Blind Study to Evaluate the Efficacy and Safety of Sandostatin ( SMS 201-995 ) in Patients With Acquired Immunodeficiency Related Diarrhea Who Were Either "Responders" or "Non-Responders" in a Prior Placebo-Controlled Double-Blind Sandostatin Study.
The Impact of a School-based WASH Intervention on Child Health and School Attendance in Addis Ababa, Ethiopia
Wells and Enteric Disease Transmission
Zinc-MNP Trial for Prevention of Diarrhea and Promotion of Linear Growth
Lao Zinc Study: Effects of Two Forms of Daily Preventive Zinc Versus Therapeutic Zinc Supplementation
Phase Legend
Key Insights
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