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Cervical Spinal Cord Injury

1
Pipeline Programs
5
Companies
5
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

5 companies ranked by most advanced pipeline stage

Angeles Therapeutics
Angeles TherapeuticsCA - Los Angeles
1 program
1
Epidural StimulationPhase 1/21 trial
Active Trials
NCT02313194Active Not Recruiting12Est. Dec 2026
MicroTransponder
MicroTransponderTX - Austin
1 program
Active VNSN/A1 trial
Active Trials
NCT05601661Completed6Est. Aug 2025
Spine BioPharma
Spine BioPharmaNY - New York
1 program
Nonsurgical treatmentN/A1 trial
Active Trials
NCT05653206Active Not Recruiting50Est. Aug 2027
Lineage Cell Therapeutics
1 program
AST-OPC1PHASE_1_21 trial
Active Trials
NCT02302157Completed25Est. Dec 2018
Vertex Pharmaceuticals
1 program
VX-210PHASE_2_31 trial
Active Trials
NCT02669849Terminated70Est. Nov 2018

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
Vertex PharmaceuticalsVX-210
Lineage Cell TherapeuticsAST-OPC1
Angeles TherapeuticsEpidural Stimulation
Spine BioPharmaNonsurgical treatment
MicroTransponderActive VNS

Clinical Trials (5)

Total enrollment: 163 patients across 5 trials

NCT02669849Vertex PharmaceuticalsVX-210

Study to Assess the Efficacy and Safety of VX-210 in Subjects With Acute Traumatic Cervical Spinal Cord Injury

Start: Jul 2016Est. completion: Nov 201870 patients
Phase 2/3Terminated
NCT02302157Lineage Cell TherapeuticsAST-OPC1

Dose Escalation Study of AST-OPC1 in Spinal Cord Injury

Start: Mar 2015Est. completion: Dec 201825 patients
Phase 1/2Completed
NCT02313194Angeles TherapeuticsEpidural Stimulation

Spinal Cord Neuromodulation for Spinal Cord Injury

Start: Jul 2013Est. completion: Dec 202612 patients
Phase 1/2Active Not Recruiting
NCT05653206Spine BioPharmaNonsurgical treatment

Incomplete Cervical SCI Without Instability

Start: Dec 2023Est. completion: Aug 202750 patients
N/AActive Not Recruiting
NCT05601661MicroTransponderActive VNS

Safety and Feasibility of Paired Vagus Nerve Stimulation With Rehabilitation for Improving Upper Extremity Function in People With Cervical Spinal Cord Injury

Start: Jun 2023Est. completion: Aug 20256 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

5 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.