Cerebral Palsy

9
Pipeline Programs
10
Companies
11
Clinical Trials
1 recruiting
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
3
0
3
1
Early DiscoveryClinical DevelopmentMarket

On Market (1)

Approved therapies currently available

Ipsen
DYSPORTApproved
botulinum toxin type a
Ipsen
Acetylcholine Release Inhibitor [EPC]injection2009

Competitive Landscape

10 companies ranked by most advanced pipeline stage

Ipsen
IpsenChina - Tianjin
3 programs
1
2
1
Botulinum toxin type APhase 31 trial
Botulinum toxin type APhase 31 trial
Botulinum toxin type APhase 21 trial
Active Trials
NCT00455637Terminated6Est. Mar 2008
NCT01249417Completed241Est. Jun 2014
NCT01251380Completed216Est. Jan 2015
Jazz Pharmaceuticals
Jazz PharmaceuticalsCA - Palo Alto
1 program
1
SativexPhase 31 trial
Active Trials
NCT01898520Completed72Est. Mar 2017
Mission Therapeutics
Mission TherapeuticsUK - Cambridge
1 program
1
umbilical cord bloodPhase 21 trial
Active Trials
NCT01988584Completed20Est. Feb 2018
Connect Biopharma
Connect BiopharmaSAN DIEGO, CA
1 program
1
umbilical cord bloodPhase 2
Verona Pharma
Verona PharmaUK - London
1 program
1
Device: Electromechanical gait trainerPhase 11 trial
Active Trials
NCT01564433Completed20Est. Jan 2012
Alliance Pharmaceuticals
1 program
1
Matched sibling donor cord blood cell infusionPhase 11 trial
Active Trials
NCT03087110Completed12Est. Dec 2020
Ottobock
OttobockNEW YORK, NY
1 program
Exopulse Mollii SuitN/A1 trial
Active Trials
NCT05885139UnknownEst. Jun 2024
Hamilton medical
Hamilton medicalSwitzerland - Bonaduz
1 program
Implementation groupN/A1 trial
Active Trials
NCT06537622Not Yet RecruitingEst. Nov 2028
Alder Therapeutics
Alder TherapeuticsSweden - Solna
1 program
Long-Term Outcomes of Hip Interventions for Children With Cerebral PalsyN/A1 trial
Active Trials
NCT04792606Recruiting1,000Est. Mar 2028
Cosmo Pharmaceuticals
Cosmo PharmaceuticalsIreland - Dublin
1 program
Powered Exoskeleton Gait TrainingN/A1 trial
Active Trials
NCT05759182CompletedEst. Nov 2024

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
Jazz PharmaceuticalsSativex
IpsenBotulinum toxin type A
IpsenBotulinum toxin type A
Mission Therapeuticsumbilical cord blood
IpsenBotulinum toxin type A
Alliance PharmaceuticalsMatched sibling donor cord blood cell infusion
Verona PharmaDevice: Electromechanical gait trainer
Hamilton medicalImplementation group
Cosmo PharmaceuticalsPowered Exoskeleton Gait Training
OttobockExopulse Mollii Suit
Alder TherapeuticsLong-Term Outcomes of Hip Interventions for Children With Cerebral Palsy

Clinical Trials (11)

Total enrollment: 1,587 patients across 11 trials

NCT01898520Jazz PharmaceuticalsSativex

A Safety, Efficacy and Tolerability Study of Sativex for the Treatment of Spasticity in Children Aged 8 to 18 Years

Start: Dec 2013Est. completion: Mar 201772 patients
Phase 3Completed
NCT01251380IpsenBotulinum toxin type A

Dysport® Pediatric Lower Limb Spasticity Follow-on Study

Start: Oct 2011Est. completion: Jan 2015216 patients
Phase 3Completed
NCT01249417IpsenBotulinum toxin type A

Dysport® Pediatric Lower Limb Spasticity Study

Start: Jul 2011Est. completion: Jun 2014241 patients
Phase 3Completed
NCT01988584Mission Therapeuticsumbilical cord blood

Safety and Effectiveness of Banked Cord Blood or Bone Marrow Stem Cells in Children With Cerebral Palsy (CP).

Start: Nov 2013Est. completion: Feb 201820 patients
Phase 2Completed
NCT00455637IpsenBotulinum toxin type A

Which is the Best Dose of Dysport in Helping With Hip Pain for Children With Cerebral Palsy?

Start: Mar 2007Est. completion: Mar 20086 patients
Phase 2Terminated
NCT03087110Alliance PharmaceuticalsMatched sibling donor cord blood cell infusion

Stem Cells in Umbilical Blood Infusion for CP

Start: Mar 2016Est. completion: Dec 202012 patients
Phase 1Completed
NCT01564433Verona PharmaDevice: Electromechanical gait trainer

Effects of Electromechanical Gait Trainer in Patients With Cerebral Palsy

Start: Nov 2011Est. completion: Jan 201220 patients
Phase 1Completed
NCT06537622Hamilton medicalImplementation group

Best Practices Fo Early Diagnosis of Cerebral Palsy

Start: Feb 2025Est. completion: Nov 2028
N/ANot Yet Recruiting
NCT05759182Cosmo PharmaceuticalsPowered Exoskeleton Gait Training

The Effects of Exoskeletal Robot-Assisted Gait Training on Children With Cerebral Palsy: A Pilot Study

Start: Sep 2024Est. completion: Nov 2024
N/ACompleted
NCT05885139OttobockExopulse Mollii Suit

Exopulse Mollii Suit, Motor Functions & CP Children With Cerebral Palsy

Start: Apr 2023Est. completion: Jun 2024
N/AUnknown
NCT04792606Alder TherapeuticsLong-Term Outcomes of Hip Interventions for Children With Cerebral Palsy

Long-Term Outcomes of Hip Interventions for Children With Cerebral Palsy

Start: Oct 2019Est. completion: Mar 20281,000 patients
N/ARecruiting

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

3 late-stage (Phase 3) programs — potential near-term approvals
1 actively recruiting trials targeting 1,587 patients
10 companies competing in this space