Cerebral Infarction

4
Pipeline Programs
3
Companies
18
Clinical Trials
2
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
0
3
Early DiscoveryClinical DevelopmentMarket

On Market (2)

Approved therapies currently available

U
CLOPIDOGREL BISULFATEApproved
clopidogrel
Unknown Company
oral2012
Sanofi
PLAVIXApproved
clopidogrel
Sanofi
oral1997

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Sanofi
SanofiPARIS, France
1 program
1
PLAVIX(clopidogrel)Phase 45 trials
Active Trials
NCT01235351Completed335Est. Sep 2011
NCT01170533Completed20Est. Aug 2010
NCT00862420Completed431Est. May 2011
+2 more trials
M&
Merck & Co.RAHWAY, NJ
1 program
1
Vorapaxar 2.5 mgPhase 21 trial
Active Trials
NCT00684515Completed90Est. Nov 2007
Gedeon Richter
Gedeon RichterHungary - Budapest
1 program
Chinese Assessment for Vinpocetine In NeurologyN/A1 trial
Active Trials
NCT01400035Completed610Est. May 2013

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Sanoficlopidogrel
Sanoficlopidogrel
Sanoficlopidogrel
Sanoficlopidogrel
Sanoficlopidogrel
Sanoficlopidogrel
Sanoficlopidogrel
Sanoficlopidogrel
Sanoficlopidogrel
Sanoficlopidogrel
Sanoficlopidogrel
Sanoficlopidogrel
Merck & Co.Vorapaxar 2.5 mg
Sanoficlopidogrel
Sanoficlopidogrel

Showing 15 of 18 trials with date data

Clinical Trials (18)

Total enrollment: 23,597 patients across 18 trials

A Study to Evaluate the Discontinuation Effect of Clopidogrel After Drug Eluting Stent Implantation in Non-diabetic Patients

Start: Oct 2007Est. completion: Jun 2008103 patients
Phase 4Completed

Safety and Efficacy of Clopidogrel for Cerebral Infarction Treatment

Start: Sep 2006Est. completion: Dec 20081,110 patients
Phase 4Completed

Clopidogrel and Aspirin Together: The Effect on C-Reactive Protein Trial

Start: Jul 2005Est. completion: Nov 2006100 patients
Phase 4Completed

Effect of Plavix on NO (Nitrogen Monoxide) Production of the Endothelial Function

Start: Dec 2002Est. completion: Apr 200439 patients
Phase 4Completed

Safety Evaluation of Clopidogrel Sulfate in Patients With Peripheral Arterial Disease

Start: Feb 2009Est. completion: May 2011431 patients
Phase 3Completed

CASPAR : Clopidogrel and Acetyl Salicylic Acid in Bypass Surgery for Peripheral ARterial Disease

Start: Sep 20041,460 patients
Phase 3Completed

Efficacy and Safety in Patients With Acute Coronary Syndrome Without ST-Segment Elevation

Start: Jul 2004800 patients
Phase 3Completed

CASTLE (Clopidogrel And Serum Troponin Level Elevation)

Start: May 2004155 patients
Phase 3Completed

Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management and Avoidance (CHARISMA)

Start: Oct 2002Est. completion: Aug 200515,603 patients
Phase 3Completed

Aortic Arch Related Cerebral Hazard Trial (ARCH)

Start: Feb 2002Est. completion: Jul 2012350 patients
Phase 3Completed

Warfarin and Antiplatelet Therapy in Chronic Heart Failure

Start: Oct 1998Est. completion: Dec 20041,587 patients
Phase 3Completed

Escalating Clopidogrel by Involving a Genetic Strategy - Thrombolysis In Myocardial Infarction 56

Start: Oct 2010Est. completion: Sep 2011335 patients
Phase 2Completed
NCT00684515Merck & Co.Vorapaxar 2.5 mg

Trial to Assess the Safety of Vorapaxar in Japanese Subjects With Cerebral Infarction (P05005; MK-5348-017)

Start: Sep 2006Est. completion: Nov 200790 patients
Phase 2Completed

Trial of Clopidogrel After Surgery for Coronary Artery Disease (CASCADE Trial)

Start: May 2006Est. completion: Jul 2009113 patients
Phase 2Completed

Mixed Antagonist of Serotonin for Claudication Optimal Therapy

Start: Feb 2006Est. completion: Dec 2007599 patients
Phase 2Completed

Platelet Aggregation Inhibition in Children on Clopidogrel (PICOLO)

Start: Jan 2004Est. completion: Apr 200692 patients
Phase 2Completed

PPI and Clopidogrel Response

Start: Mar 2009Est. completion: Aug 201020 patients
Phase 1Completed
NCT01400035Gedeon RichterChinese Assessment for Vinpocetine In Neurology

Chinese Assessment for Vinpocetine In Neurology

Start: May 2010Est. completion: May 2013610 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

3 companies competing in this space